|Overview of Medications
Alternative Medicine, Herbs, Vitamins and Scleroderma
Anesthesia Considerations for Systemic Sclerosis (SSc, or Scleroderma)
Medicinal Metals: Gold, Platinum
FDA Warnings on Medications and Treatments
Therapeutic Plasma Exchange.
Vaccinations and Scleroderma
There are a variety of medications used for scleroderma, arthritis, and autoimmune and rheumatic diseases. Which medication to use is dependent upon factors such as the patient, the symptoms, the doctors, and in some cases, the patient's insurance company (what is approved and what isn't).
This section covers specific medications generally used to treat these diseases as well as alternative treatments that have been proven to relieve some of the symptoms associated with scleroderma. It also covers some of the treatments that have proven to be ineffective for scleroderma and other rheumatic diseases. (Also see Scleroderma Clinical Treatments and Clinical Trials)
Treatment of Rapidly Progressive Systemic Sclerosis (SSc): Current and Futures Perspectives. Novel agents capable of modulating fibrotic and inflammatory pathways involved in SSc pathogenesis are currently under development for the treatment of rapidly progressive SSc. PubMed, Expert Opin Orphan Drugs, 2016;4(1):31-47.
Autoimmunity. Autoimmune disease is a disorder that occurs because of autoimmunity--a disease that is caused by an immune response to the body of the patient himself or herself. There are several ways to treat autoimmune diseases. ISN.
Specific Drug Information Prescription drug information for consumers and professionals. Drugs.com
Video: Avoiding Medication Mistakes. Taking the wrong medication or the wrong dose can be an easy mistake to make. It can also be life threatening. In this Consumer Update video, FDA Drug Safety Expert, Cindi Fitzpatrick, R.N., provides tips on avoiding medication mistakes. FDA.
Does grapefruit affect my medicine? Eating grapefruit or drinking grapefruit juice can affect some medicines and in most cases, it increases the level of the medicine in your blood. NHS Choices, 05/12/2015. (Also see Food Guide)
Scleroderma and Alternative Medicine, Herbs, and Vitamins What natural, healthy things can you do to help improve scleroderma? ISN.
Diet and Systemic Scleroderma
Food Guide for Autoimmune Disease
|Supplement Guide for Scleroderma
Know Your Symptoms
Traditional Chinese Medicine (TCM)
Alternative Medicine Links
Anesthesia Considerations for Systemic Sclerosis (SSc, or Scleroderma). Care should be taken to select the best anesthetic or analgesia for systemic sclerosis (scleroderma) patients, with consideration of their entire medical history plus general risk factors for scleroderma. ISN.
Avoid Steroids, Prednisone
Manage Cardiac and Vascular Issues
|Manage Gastrointestinal Issues
Antibiotic interaction may raise heart death risk. Doctors have known for years that the antibiotic erythromycin can, in rare cases, spark an abnormal and sometimes fatal heartbeat. However, combining it with several common drugs--Cardizen, Diltiazem, Tiazac, Dilacor, verapamil, Calan, Isoptin --may dramatically worsen that risk. Expired article from The New Zealand Herald.  (Also see Hypertension)
Urgent care centers overprescribe antibiotics, study finds. Urgent care centers are the biggest offenders when it comes to giving people antibiotics they don’t need, researchers reported. NBC News, 07/16/2018.
In a Dragon’s Blood, Scientists Discover a Potential Antibiotic. Biochemists may have discovered a type of antibiotic that sounds like something out of a fairy tale: it is based on dragon blood. New York Times, 04/17/2017.
Little evidence that antibiotics help open surgical wounds heal. There are no high–quality trials assessing whether using antibiotics or antiseptics on open surgical wounds speeds healing by slowing the growth of dangerous microorganisms, according to a new Cochrane review. Reuters Health, 10/07/2016.
Antibiotics Are Still Overused in Hospitals. The most comprehensive study yet shows that antibiotic use hasn’t changed in hospitals, despite recent warnings that they drugs are overprescribed. Time Healthland, 09/19/2016.
Superbug review says more vaccines needed to reduce antibiotic use. More use of vaccines would reduce the need to use antibiotics and help fight the rise of drug–resistant superbug infections, according to a British government–commissioned review of the threat. Reuters Health, 02/11/2016. (Also see Vaccinations)
Newly Discovered Bacteria Can Resist All Antibiotics. A mutation discovered in people and livestock in China makes bacteria resistant to last-resort drugs. Time Healthland, 11/19/2015.
Endocannabinoid System The Endocannabinoid System (ECS) is the name for a series of endogenous cell receptors that respond to certain kinds of agonists, known as Cannabinoid Receptor 1 (CB1), which are abundant in the central nervous system and Cannabinoid Receptor 2 (CB2), which are more often found on immune cells, in the gastrointestinal tract, and in the peripheral nervous system. ISN.
–Marijuana (Cannabis sativa)
The value of glucocorticoid co-therapy in different rheumatic diseases--positive and adverse effects. There is an ongoing quest for new drugs with glucocorticoid actions without the potential to cause harmful effects, such as selective glucocorticoid receptor agonists. PubMed, Arthritis Res Ther.
Imiquimod: Potential risk of an immunostimulant. This case highlights the potential risk of using imiquimod cream (an immunostimulant) in a patient who has a condition requiring immunosuppression, such as autoimmune disease or an organ transplant. PubMed, Australas J Dermatol.
Mainstream Medications are the pharmaceuticals that are normally prescribed by rheumatologists for the treatment of scleroderma and other rheumatic diseases. ISN.
FDA Warnings and Recalls
Gold and some other metals have been proven to suppress the inflammatory process. DMARDs such as Auranofin and Gold sodium thiomalate are forms of gold used to treat rheumatic diseases such as rheumatoid arthritis. ISN.
FDA warnings and alerts have been issued for some of the medications and treatments used for scleroderma and other rheumatic disease. ISN.
Scleroderma Treatments and Clinical Trials. There have been significant advances in scleroderma treatment research. This research has led to treatments that not only improve the symptoms, but the overall quality of life. ISN.
—Symptoms and Treatments
Therapeutic Plasma Exchange. Therapeutic plasma exchange (TPE) is a treatment that removes plasma from your blood, which is then replaced with a substitute. Plasma is the liquid portion of blood which helps carry blood cells and other substances throughout your body. Plasma exchange (plasmapheresis) is a way of separating plasma from blood cells. ISN
TPE for Scleroderma
|TPE for Other Diseases|
Vaccinations such as flu shots and pneumonia shots are recommended for patients with scleroderma and other autoimmune diseases. However, before receiving a vaccination of any kind, patients should consult their physicians.
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