Treatments for Symptoms of Sjogren's Syndrome

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Treatments of Sjogren's: Overview
Treatments for Dry Eyes
Treatments for Dry Mouth
Treatment for Fatigue
Treatment for Renal Involvement

Overview of Treatments for Sjogren's

Treatments for Sjogren's may consist of therapies aimed at relieving specific symptoms, such as dry eyes or dry mouth, or targeted at trying to control the underlying disease process.

Clinical Trials: Sjögren's Syndrome. CenterWatch

Dry.Org - Internet Resources for Sjögren's Syndrome Dry.Org

A Meta–Analysis of Treatment for Primary Sjögren's Syndrome. Reducing inflammation potentially improves salivary gland function. No individual immunomodulatory drug demonstrated consistent benefit in xerostomia and xerophthalmia. PubMed, Arthritis Care Res (Hoboken), 05/06/2019.

Optimizing conventional DMARD (cDMARD) therapy for Sjögren's syndrome (pSS). The unique and potent mechanisms of action to target immunopathology in pSS suggests that optimizing cDMARDs for treatment of pSS is worthwhile. ScienceDirect, Autoimmun Rev, 2018 May;17(5):480-492. (Also see DMARDs)

Treatments for Dry Eyes

Dry Eyes: Artificial Tears, Dry Eyes, Tears Naturale, Refresh, Refresh Plus, HypoTears, Lacrisert artificial tear inserts.

Gen-Teal Gel by CIBA Vision is an over-the-counter gel for dry eyes. It is best used at night, or along with liquid drops, as it can cause blurriness.

Treatments for Dry Mouth

Dry Mouth: Biotene products such as toothpaste, mouthwash, and gel; Salivert, Optimoist, Saliva Substitute, Moi-Stir, and Salix Lozenges.

Evoxac. This medication is used to treat symptoms of dry mouth due to Sjogren's Syndrome. MedicineNet.

Scleroderma Dental Involvement. Systemic scleroderma sometimes affects the mouth, teeth, jaw, and gums. It can cause the mouth to shrink, tooth loss, mouth sores, dry mouth, and jaw pain from TMJ. ISN.

Bone Resorption
Candida (Fungal)
Dental Amalgam
Dental Fears/Phobias
Dental Implants
General Dentistry
Microstomia (Small Mouth)
Microstomia Stories
Mouth Sores
Periodontal Disease
Photos of Dental Involvement
Scleroderma Dental
Sensitive Teeth
Stories of Scleroderma Dental
Sjogren's Syndrome
Taste and Smell
Tongue and Oral Cancers
Trigeminal Neuralgia
Xerostomia (Dry Mouth)

Treatments for Fatigue

Supervised walking improves cardiorespiratory fitness, exercise tolerance, and fatigue in women with primary Sjögren's syndrome (pSS): a randomized-controlled trial. This supervised walking program was demonstrated to be feasible and safe with improvements in cardiorespiratory fitness, exercise tolerance, fatigue, and patient perception of improvement in pSS patients. PubMed, Rheumatol Int, 2019 Feb;39(2):227-238.

Treatments for Renal Involvement

Kidney Failure. Lifelong efforts to control blood pressure and diabetes may be the best way to prevent chronic kidney disease and its progression to kidney failure. Usually, kidney function gradually decreases over time.

Go to Sjogren's Syndrome: Stories

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