Scleroderma Types Systemic Symptoms Eyes

Eye Involvement

ISN Guide to Eye Involvement: Dr. Liz Irvin

Hello, I am Dr. Liz Irvin, your ISN Guide to Eye Involvement. In addition to helping Dr. C. Stephen Foster develop resources for this section of the ISN website, I am happy to try to respond to questions that you may have or to redirect you to resources that may be helpful. Email [email protected].

Overview of Eye Involvement in Scleroderma (Systemic Sclerosis)

Eye symptoms and diseases that may be related to scleroderma include normal tension glaucoma, autoimmune iritis or uveitis, and types of optic neuropathy.

Ocular Inflammatory Disease

A Patient Guide to Ocular Inflammatory Disease. This is an online guide, covering symptoms, diagnosis and treatment for inflammatory eye diseases. In addition, printed copies of this guide can be requested free of charge from the Ocular Immunology and Uveitis Foundation. (Also see Dr. C. Stephen Foster, ISN Medical Advisory Board)

Normal Tension Glaucoma (NTG)

Normal Tension Glaucoma. Normal Tension Glaucoma (NTG) is when the optic nerve is damaged even though the pressure inside of the eye is normal. ISN.

Autoimmune Iritis or Uveitis (Eye Inflammation)

Autoimmune Iritis or Uveitis. When inflammation affects the eyes, it is called different things depending on which part of the eye it affects (the iris or the uvea). ISN.

Optic Neuropathy

Optic Neuropathy is a general term used for damage to the optic nerve regardless of the cause of the damage. ISN.

Other Eye Diseases of Scleroderma

A Wide Spectrum of Ocular Manifestations Signify Patients with Systemic Sclerosis (SSc). Eyelid skin abnormalities, dry eye disease and retinal abnormalities are among the most common SSc-related ocular involvements. PubMed, Ocul Immunol Inflamm, 2019 Oct 2:1-9.

Case Report: Surgical management of raised intra–ocular tension in the hostile ocular surface – recurrent tube erosion in a patient with systemic sclerosis. In patients with systemic disease such as scleroderma, pre–operative immunosuppression helps to reduce the of erosion in difficult cases. PubMed, BMC Ophthalmol.

Evaluation of Changes in Corneal Biomechanics in Patients with Systemic Sclerosis. In the course of the disease SSc leads to various alterations in connective tissue, which can also involve corneal tissue. PubMed, Klin Monbl Augenheilkd, 03/07/2018.

Case Report Highlights Acute Central Retinal Vein Occlusion (CRVO) in Scleroderma Patient The research team thoroughly analyzed other causes of CRVO besides scleroderma, concluding that scleroderma was the most likely cause for this patient’s condition. Scleroderma News.

Localized Scleroderma (Morphea, Linear, En Coup de Sabre)

Prospective study to evaluate the clinical and radiological outcome of patients with scleroderma of the face. Patients with localized scleroderma of the face have a high prevalence of neurological and ophthalmological changes. All cases of localized scleroderma of the face should be thoroughly examined for the presence of systemic changes. PubMed. (Also see Types of Scleroderma, Localized Scleroderma, Neurological Involvement)

Pellucid Marginal Degeneration and Systemic Sclerosis (Scleroderma)

(Case Report) Pellucid marginal degeneration and scleroderma. Pellucid marginal degeneration is characterized by non-inflammatory and progressive peripheral corneal thinning inferiorly, often with high against-the-rule astigmatism. PubMed, Clin Exp Optom.

Pyoderma Gangrenosum and Systemic Sclerosis (Scleroderma)

Sclerokeratitis and facial skin lesions: a case report of pyoderma gangrenosum and its response to dapsone therapy. Pyoderma gangrenosum is a rare autoimmune disorder that can affect the eye. Biopsy of affected tissue is the key to diagnosis. Immunomodulating therapy can be a useful adjunct to the traditional steroid therapy. PubMed, Cornea.

Retinopathy and Systemic Sclerosis (Scleroderma)

Purtscher's retinopathy in scleroderma. We report a unique case of a 37-year-old patient, a known case of scleroderma, complaining of bilateral acute visual disturbance, which was diagnosed later on as Purtscher's retinopathy. PubMed, GMS Ophthalmol Cases, 2019 Mar 1;9:Doc07.

(Case Reports) Acute retinal artery occlusion in systemic sclerosis: A rare manifestation of systemic sclerosis fibroproliferative vasculopathy. We describe the clinical features, laboratory and ancillary examinations of the three patients with SSc who developed acute unilateral blindness. Seminars in Arthritis and Rheumatism.

Eye Involvement of Rheumatic Diseases

Support for Eye Diseases

SCLERO.ORG is the world's leading nonprofit for trustworthy research, support, education and awareness for scleroderma and related illnesses. We are a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team. Donations may also be mailed to: