Graft-versus-Host Disease (GVHD)

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Patient Stories

Overview of Graft-versus-Host Disease (GVHD)

GVHD KaleidoscopeGraft-versus-Host Disease (GVHD) is an autoimmune response to foreign cells, such as from skin grafting, bone marrow transplants, stem cell transplants, blood transfusions, or organ transplants.

Causes of Graft-versus-Host Disease (GVHD)

Graft-versus-Host Disease - Causes. Graft-versus-host disease (GVHD) is a complication that can occur after a stem cell or bone marrow transplant in which the newly transplanted material attacks the transplant recipient's body. MedlinePlus.

Diagnosis of Graft-versus-Host Disease (GVHD)

Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Our data points to the potential of NET-associated proteins to serve as biomarkers and NET-dismantling biologics (heparin eye drops) as treatment for oGVHD. PubMed, Ocul Surf, 2019 Jul;17(3):589-614.

Bullous scleroderma-like changes in chronic graft-versus-host disease. Chronic cutaneous GVHD is categorized according to the type of skin lesions into lichenoid and sclerodermoid variants, but bullous scleroderma-like changes are exceptional. PubMed, J Eur Acad Dermatol Venereol.

Treatments for Graft-versus-Host Disease (GVHD)

Feasibility of extracorporeal photopheresis in pediatric patients with graft-versus-host disease after hematopoietic stem cell transplantation. We found ECP to be a feasible and safe treatment, and particularly, children with aGVHD appeared to respond well to ECP. PubMed, Pediatr Transplant, 2019 Apr 11:e13416.

A case of cutaneous lichen sclerosus et atrophicus (LSA) effectively treated by extracorporeal photochemotherapy (ECP). The fact that ECP is effective in LSA, graft-versus-host disease (GVHD), erosive lichen planus, and scleroderma strengthen the hypothesis that there is a common link between these four conditions. Wiley. Photodermatology, Photoimmunology & Photomedicine. (Also see Lichen Sclerosus)

Patient Stories for Graft-versus-Host Disease (GVHD)

Blog: Jackie Sue We Love You. Jackie passed away on November 30th, 2011. Jackie had GVHD. The blog covered her progress after her mini-allo MUD transplant. Her transplant was the first one to be performed by the Mayo Clinic. Bruce and Jackie. (Also see Graft vs. Host Disease, GVHD)

Klaas: Scleroderma Graft-vs-Host Disease (GVHD) So I would like to know if, and when, I will be able to walk again…

(Spanish/Español) Klaas: Sclerodermia da GVHD Essiste un modo per capire se ci sono delle speranze e quali sono…

(Italiano) Fabiola: Paziente Affetta da Sclerodermia Morphea Dopo 5 anni si e' svegliata una sclero conseguenza pero' della GVHD (Graft Versus Host Disease) che viene dopo il trapianto di midollo…

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