Systemic Autoimmune Rheumatic Diseases

Author: Janey Willis. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer


Rheumatic KaleidoscopeSystemic autoimmune rheumatic diseases are different from most autoimmune diseases in that they affect many organs, cells or tissues simultaneously rather than just one. Examples of rheumatic diseases are systemic sclerosis (systemic scleroderma), lupus, rheumatoid arthritis, Sjögren's, dermatomyositis, and polymyositis. Examples of non-rheumatic diseases are diabetes, autoimmune hepatitis, autoimmune thyroid disease, and psoriasis.

The National Data Bank (NDB) for rheumatic diseases: Diagnosis List. If you have been diagnosed with one or more conditions from the following list, you are eligible to participate in NDB research. If you have a diagnosis for a rheumatic disease that you do not see listed, please contact us. The NDB for Rheumatic Disease. (Also see Research Registries)

Symptoms and Complications of Autoimmune Rheumatic Diseases

Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune (IA) rheumatic diseases: a multicentric matched cohort study. In hospitalised patients with chronic inflammatory rheumatic diseases, having a connective tissue disease but not IA nor previous immunosuppressive therapies was associated with severe COVID-19. BMJ Journals, Annals of Rheumatic Diseases, 08/12/2020.

Chronic Q fever associated with Systemic Sclerosis (SSc). Chronic Q fever preceding SSc was associated with a milder course of SSc without the necessity of immunosuppressive drugs, while chronic Q fever development due to immunocompromised state was associated with a more deteriorating course of SSc. PubMed, Eur J Clin Invest, 2019 May 11:e13123.

Ocular Involvement in Systemic Autoimmune Diseases. The aim of this review is to elucidate to non-ophthalmologists the major ocular complications of rheumatic diseases and their specific management and treatment options. PubMed, Clin Rev Allergy Immunol. (Also see Eye Involvement of Rheumatic Diseases)

Depression, anxiety, and quality of life in a large cohort of patients with rheumatic diseases: common, yet undertreated. For the management of depression and anxiety, an increased awareness among physicians dealing with rheumatologic patients is warranted in order to integrate detection and effective treatment of anxiety and depression into the routine clinical practice. PubMed, Clin Rheumatol. (Also see Depression)

Eye Involvement. ISN

Symptoms and Complications of Scleroderma. ISN.

Symptoms and Complications of Lupus. ISN.

Symptoms and Complications of Dermatomyositis and Polymyositis. ISN.

Symptoms and Complications of Sjögren's. ISN.

Symptoms and Complications of Rheumatoid Arthritis. ISN.


Mini-Review: Human Microbiome and Rheumatic Diseases. We review the role of various human microbiota on the pathogenesis of rheumatic diseases, focusing on spondylarthritis and rheumatoid arthritis. PubMed, Clin Rheumatol, Front Cell Infect Microbiol, 2020 Nov 10;10:491160.


Diagnosis of Scleroderma. ISN.

Diagnosisof Lupus. ISN.

Diagnosisof Dermatomyositis and Polymyositis. ISN.

Diagnosisof Sjögren's. ISN.

Diagnosisof Rheumatoid Arthritis. ISN.


Autoantibodies in Systemic Rheumatic Diseases. Specialized blood tests such as antinuclear antibody (ANA) tests are sometimes useful in the diagnosis or categorization of both localized and systemic scleroderma, as well as overlapping or other autoimmune diseases. ISN.

Rheumatic Disease Autoantibodies in Patients with Autoimmune Thyroid Diseases (ATD). We found rheumatic autoantibodies in 17.5% of ATD patients without rheumatic diseases and there was no clinical rheumatic disorder during the period of five years. PubMed, Med Princ Pract, 06/04/2018. (Also see Thyroid Diseases)


Treatments for Rheumatic Diseases. ISN.

Go to Rheumatoid Arthritis

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