Pancreatitis, Autoimmune (AIP)

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AIP and Other Diseases


Pancreatitis KaleidoscopeAutoimmune pancreatitis is a chronic pancreatitis that is usually treated with corticosteroids, and that has recently been found to be more systemic than previously thought in that it can affect organs other than the pancreas. ISN.

Autoimmune Pancreatitis. Autoimmune pancreatitis is a recently recognized inflammatory disorder that can affect not only the pancreas, but also the bile ducts, salivary glands, kidneys and lymph nodes. The disease occurs when your immune system mistakenly attacks healthy tissue, causing ongoing inflammation and potentially serious complications. MayoClinic.

Autoimmune Pancreatitis and Other Diseases

Hypothyroidism in patients with autoimmune pancreatitis. Further studies are necessary to clarify whether this subclinical hypothyroidism is another manifestation of IgG4-RD. PubMed, World J Gastrointest Pharmacol Ther, 2018 May 6;9(2):16-21. (Also see Thyroid Diseases)

Systemic Lupus Erythematosus-Related Pancreatitis in Children: Severe and Lethal Form. Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease of unknown cause and its occurrence in children is rare, and acute pancreatitis is exceptional in this matter. PubMed, Case Rep Pediatr, 2018 Dec 31;2018:4612754. (Also see Lupus in Overlap and Complications)

Causes of AIP

Causes of Autoimmune Pancreatitis. Autoimmune pancreatitis, also called AIP, is a chronic inflammation that is thought to be caused by the body's immune system attacking the pancreas and that responds to steroid therapy. Two subtypes of AIP are now recognized, type 1 and type 2. Mayo Clinic.

Diagnosing AIP

A Diagnostic Challenge: Pancreatic Cancer or Autoimmune Pancreatitis? This case highlights the challenge in the diagnostic approach of a pancreatic mass. PubMed, Curr Health Sci J, 2018 Apr-Jun;44(2):181-185.

Comparison of clinical characteristics of radiological forms of autoimmune pancreatitis (AIP). Diffuse–type and head–type AIP patients had similar clinical features. The body and/or tail–type group differed significantly from the other two types. PubMed, HPB (Oxford), 05/26/2018.

Case Report: Diagnosis of autoimmune pancreatitis (AIP) with cholesterol granuloma (CG) mimicking intraductal papillary–mucinous carcinoma. Although preoperative diagnosis may be difficult, AIP with CG should be considered as a differential diagnosis in pancreatic cysts involving nodular lesions. PubMed, Int J Surg Case Rep.

Treating AIP

Risk factors and treatment of relapses in autoimmune pancreatitis: Rituximab is safe and effective. In relapsing autoimmune pancreatitis, rituximab is more efficient than immunomodulator drugs and shows better tolerance. PubMed, United European Gastroenterol J, 2019 Oct;7(8):1073-1083. (Also see Biologic Agents)

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