Hello, I am Janey Willis, ISN Guide to Diabetes. Type 1 Diabetes is an autoimmune disease, and Type 2 Diabetes is caused by risk factors such as lifestyle, ethnicity, age, and pregnancy. The majority of diabetics have Type 2. See Disclaimer.
|Overview of Treatments
Treatments for Complications
Pancreas and Islet Transplants
Stem Cell Transplant
All people with Type 1 Diabetes need to take insulin because their bodies do not make enough of it. Managing diabetes with diet and exercise is also important. In some cases, pancreas transplants or islet transplantation are considered to control one's diabetes. (Also see Autoimmune Diseases and Overview of Diabetes)
Treatments. This resource is designed to be used with forms that you can print out and personalize to meet your individual needs. National Diabetes Information Clearinghouse.
When Good Guys Turn Bad: Bone Marrow's (BM) and Hematopoietic Stem Cells'(HSPCs) Role in the Pathobiology of Diabetic Complications. In this review, we will discuss the most recent literature on the molecular mechanisms underpinning hyperglycemia-mediated BM dysfunction and differentiation abnormality of HSPCs. PubMed, Int J Mol Sci, 2020 May 29;21(11):3864.
Anti-interleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial. Our results suggest the concept that IL-1 inhibition may be considered a targeted treatment for RA and T2D. PubMed, PLoS Med, 2019 Sep 12;16(9):e1002901. (Also see Treatments for Rheumatoid Arthritis)
Vitamin D fights cancers and diabetes, is the pivotal feedstock for a hormone that protects muscle, and inhibits autoimmune disorders from multiple sclerosis and lupus to inflammatory bowel disease. Expired article from Science News Online. (Also see Causes of Scleroderma: Vitamin D Deficiency)
Real–Life Management and Effectiveness of Insulin Pump with or Without Continuous Glucose Monitoring in Adults with Type 1 Diabetes. In a real–world setting, sensor augmented pump therapy is associated with more self-adjustments of insulin therapy when compared to continuous subcutaneous insulin infusion alone. PubMed, Diabetes Ther, 2019 Jun;10(3):929-936.
Diabetes: How lifestyle and daily routine affect blood sugar. You can keep your blood sugar within target range and prevent diabetes complications by knowing what makes your blood sugar rise and fall. Take a look at the day-to-day factors that can cause your blood sugar to rise and fall. Then find out how to cope with them. MayoClinic.
Fish oil pills 'no benefit' for type 2 diabetes. People with type 2 diabetes "should not be encouraged" to take omega-3 fish oil supplements, researchers from the University of East Anglia say. BBC Health News, 08/22/2019. (Also see Supplement Guide)
Early efficacy of islet transplantation in the treatment of adult advanced diabetes. Islet transplantation is effective in the treatment of advanced diabetes patients with small trauma and high safety, which is worthy of more promotion. PubMed, Zhonghua Yi Xue Za Zhi, 2020 Jul 14;100(26):2040-2043.
Glycemic variability indices can be used to diagnose islet transplantation (IT) success in type 1 diabetic patients. The proposed thresholds allow an easy evaluation of IT success using only continuous glucose monitoring data and may be a clinical tool for the follow-up of transplanted patients. PubMed, Acta Diabetol, 10/10/2019.
Beta–cell therapies for type 1 diabetes: Transplants and bionics. This article reviews the current state of beta–cell replacement through transplant of the whole pancreas or of islet cells. PubMed, Cleve Clin J Med, 2018 Dec;85(12):931-937.
Using Mesenchymal Stromal Cells in Islet Transplantation. This approach has the potential to overcome many of the technical and regulatory hurdles associated with using MSCs as an adjuvant therapy for human islet transplantation. PubMed, Stem Cells Transl Med, 2018 Aug;7(8):559-563.
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