Hello, I am Janey Willis, ISN Guide to Diabetes. Type 1 Diabetes is an autoimmune disease, and Type 2 Diabetes is caused by risk factors such as lifestyle, ethnicity, age, and pregnancy. The majority of diabetics have Type 2. See Disclaimer.
|Clinical Trials for Diabetes||Research on Diabetes|
Clinical trials give patients the opportunity to try treatments that are still in development. Ask your diabetic specialist if there are any clinical trials suitable for you. (Also see Autoimmune Diseases and Overview of Diabetes)
Soluble Antigen Arrays (SAgAs) Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes. SAgAs offer a novel and promising Antigen-specific immunotherapy platform superior to soluble peptides in inducing tolerance while mitigating risks of anaphylaxis for the treatment of T1D. PubMed, Diabetes, 2021 Jan 19;db200845.
Distinct Phenotypes of Islet Antigen-specific CD4+ T Cells Among the Three Subtypes of Type 1 Diabetes. The phenotypes of islet antigen-specific CD4+ T cells differed among the three T1D subtypes. PubMed, J Clin Endocrinol Metab, 07/11/2020.
Polyglandular autoimmunity in autoimmune thyroid disease (AITD) behaves differently from polyglandular autoimmunity in type 1 diabetes. AITD shows clustering of gastric autoimmunity with celiac and adrenal autoimmunity, which is consistent with the proposed entity of the autoimmune polyglandular syndrome type 2. J. Wiebolt. (Also see Thyroid Disease)
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