Behçet's is quite likely an autoimmune disease, and a type of vasculitis. It is not contagious. It can cause mouth and genital sores, eye inflammation, arthritis, and even heart problems. It is not curable. It is usually treated with immunosuppressant medications. (Also see Autoimmune Diseases and Vascular Involvement)
Increased Cardiovascular (CVD) Risk and All-cause Death in Patients With Behçet Disease (BD): A Korean Nationwide Population-based Dynamic Cohort Study. Patients with BD must be carefully monitored for the potential development of CVD to ensure that appropriate early treatments are delivered. PubMed, J Rheumatol, 2020 Jun 1;47(6):903-908.
The Frequency of Fibromyalgia (FM) and its Relationship With Disease Activity in Female Patients With Behçet's Disease (BD): A Cross Sectional Study. Disease activity is higher in female BD patients with FM than those without FM. PubMed, Arch Rheumatol, 2020 Jan 8;35(3):401-408. (Also see Fibromyalgia)
Is Helicobacter pylori associated with Behçet's syndrome (BS)? A meta-analysis. BS patients had higher rate of H pylori infection, and clinical symptoms can be improved after H pylori eradication. PubMed, Helicobacter, 2019 Dec;24(6):e12663.
Critical role of neutrophil extracellular traps (NETs) in patients with Behçet's disease . Our data show that NETs and markers of NETS levels are elevated in patients with BD and contribute to the procoagulant state. PubMed, Ann Rheum Dis, 05/30/2019.
Most Common Symptoms and Signs of Behçet's Disease. Behçet's disease is not contagious; it is not spread from one person to another. The four most common symptoms (as listed) are mouth sores, genital sores, inflammation inside of the eye, and skin problems. American Behçet's Disease Association.
(Case Report) A case study of Neuro-psycho-Behçet's Syndrome presenting with psychotic attack.. To our knowledge, this is the first case report of Neuro-Behçet's Syndrome that presents with an acute psychotic attack. PubMed, Clin Neurol Neurosurg.
(Case Report) Neuro-Behçet's disease presenting with amnesia and frontal dysfunction. We report a 48-year-old patient with neuro-Behçet's disease who presented with the combination of severe memory impairment and frontal/executive dysfunction. PubMed, Clin Neurol Neurosurg.
(Case Report) Behçet's disease (BD) associated with celiac disease (CD): a very rare association. There are common findings between Behçet's disease (BD) and celiac disease (CD); however, association in the same patient is a rarity. We relate the third case in the literature of this overlap in a 40-year-old woman with history of obstipation since her childhood. Ascertaining whether pathogenic mechanisms are common in these two conditions requires further investigation. Rheumatology International. (Also see Celiac Disease)
Behçet's Disease: Causes. Doctor's don't know what causes Behçet's disease. Many believe Behçet's disease is a form of autoimmune disorder. Behçet's disease is likely caused by a combination of genetic and environmental factors. Mayo Clinic.
KIR3DL1/S1 Allotypes Contribute Differentially to the Development of Behçet Disease. To our knowledge, this is the first analysis of KIR3DL1/S1 allelic variation in Behçet disease and may provide insight into the pathogenic role of HLA-B*51 and its interaction with KIR3DL1/S1. PubMed, J Immunol, 08/12/2019.
Associations between vitamin D receptor polymorphisms and susceptibility to Behçet's disease: A meta–analysis. This meta–analysis demonstrated the association between FokI and ApaI polymorphisms in VDR gene with the risk of BD. PubMed, Immunol Invest, 2018 Feb 1:1-14. (Also see Vitamin D Deficiency)
Screening and Diagnosis. No tests can determine definitively whether or not you have Behçet's disease. Instead, your doctor relies primarily on your signs and symptoms to diagnose Behçet's disease. Mayo Clinic.
Circulating prolactin levels and Behçet's disease: A meta–analysis. This meta–analysis of current evidence suggests that circulating prolactin levels may not be higher in patients with BD than in controls. PubMed, Cell Mol Biol (Noisy-le-grand), 2018 Jan 31;64(1):14-18.
Treatments for Behçet's Disease. There is no cure for Behçet's disease. Treatment typically focuses on reducing discomfort and preventing serious complications. Corticosteroids and other medications that suppress the immune system may be prescribed to treat inflammation. American Behçet's Disease Association.
SCLERO.ORG is the world's leading nonprofit for trustworthy research, support, education and awareness for scleroderma and related illnesses. We are a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team. Donations may also be mailed to: