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Autoimmunity

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview
Human Immune System
Causes
Diagnosis
Polyautoimmunity
Symptoms
Treatments
Autoimmunity and Other Diseases

Overview: What is Autoimmunity?

Autoimmune  KaleidoscopeThe human immune system is designed to continually thwart invasions of hostile germs and substances. Sometimes the immune system attacks its own bodily tissues, instead of the foreign invaders. This is called "autoimmunity". There are over 80 autoimmune diseases. Most of them predominantly affect females.

What is Autoimmunity? The healthy human body is equipped with a powerful set of tools for resisting the onslaught of invading microorganisms. Unfortunately, this set of tools, known as the immune system, sometimes goes awry and attacks the body itself. At least ten million Americans suffer from the more than eighty illnesses caused by autoimmunity. John Hopkins Medical Institutions. (Also see Autoimmune Diseases and Antibodies)

Autoimmunity. Welcome to Ed's Pathology Notes, placed here originally for the convenience of medical students at my school. I am good at helping people find resources and answers.

Coronavirus and autoimmune disease: Are YOU at risk? Coronavirus is causing a great deal of anxiety, particularly for vulnerable groups of people including the elderly and those with autoimmune disease. Express Health, 03/18/2020.

Human Immune System

WinterThe Human Immune System is a defence mechanism that protects the body against disease. ISN

Overview
Acquired Immune
Brain and Immune
Endocannabinoid
Innate Immune
Interstitial Immune
Neuroimmune
Psychological Immune

Causes of Autoimmunity

Mesenchymal stromal cells (MSC) for systemic sclerosis treatment. This review aims to summarize acquired knowledge in the field of MSC definition and in vitro and in vivo functional properties. PubMed, Autoimmun Rev, 2021 Jan 18;102755.

Diagnosis of Autoimmunity

Autoimmune Disease: Types, Causes, Symptoms and More. An autoimmune disease is a condition in which your immune system mistakenly attacks your body. The immune system normally guards against germs like bacteria and viruses. When it senses these foreign invaders, it sends out an army of fighter cells to attack them. Healthline.

Polyautoimmunity

Polyautoimmunity in Sjögren's Syndrome. Polyautoimmunity is a frequent condition in Sjögren syndrome (SS) and follows a grouping pattern and the study of polyautoimmunity provides important clues for elucidating the common mechanisms of autoimmune diseases. PubMed, Rheum Dis Clin North Am. (Also see Sjögren's Syndrome)

Symptoms of Autoimmunity

Psychotic and nonpsychotic mood disorders in autoimmune encephalitis: diagnostic issues and research implications. Recent research on autoimmune disorders suggests additional links between systemic and central nervous system (CNS) pathophysiology, among which the identification of antibody-induced limbic encephalitis provided the strongest evidence for the potential involvement of autoimmunity in the pathogenesis of severe mood and psychotic symptoms. Neuro Immunology and Inflammation.

Treating Autoimmunity

Most autoimmune diseases are treated by rheumatologists. For many diseases, it's important to find a rheumatologist that specializes in it -- and most especially for the rarer and harder to treat autoimmune diseases, such as dermatomyositis and scleroderma.

Autoimmunity and Other Diseases

The Functional Roles and Applications of Immunoglobulins (Igs) in Neurodegenerative Disease. We summarize the functional roles of Igs with respect to neurodegenerative disease, focusing on the target antigens and effector cell types. PubMed, Int J Mol Sci, 2020 Jul 26;21(15):5295.

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