Autoimmune Diseases

Ankylosing Spondylitis

Ankylosing Spondylitis

Ankylosing Spondylitis is a type of arthritis that primarily affects the spine and pelvis.

The Risk and Consequences of Vertebral Fracture (VF) in Patients with Ankylosing Spondylitis (AS): A Population-based Data Linkage Study. The significantly increased risk of VF in patients with AS has not altered following the introduction of tumor necrosis factor inhibitor treatment. PubMed, J Rheumatol, 2020 Nov 1;47(11):1629-1636.

Effects of exercise programmes on pain, disease activity and function in ankylosing spondylitis (AS): A meta-analysis of randomized controlled trials. For patients with AS, exercise programmes improve pain, function and disease activity. PubMed, Eur J Clin Invest, 2020 Jul 19;e13352.

Comparative Persistence of Methotrexate (MTX) and Tumor Necrosis Factor Inhibitors (TNFi) in Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis. Concomitant use of MTX with a TNFi, however, is associated with improved TNFi persistence in all 3 diseases. PubMed, J Rheumatol, 2020 Jun 1;47(6):826-834. (Also see Treatments for Rheumatoid Arthritis, Psoriasis and Psoriatic Arthritis and Immunosuppressants)

(Case Report) Coexistence of Ankylosing Spondylitis (AS) With Morphea. Morphea and AS with an inflammatory background and active immunity can exist in the same patient and recent studies have showed the importance of Th17 and associated cytokines in the pathogenesis of these two diseases. Archives of Rheumatology. (Also see Morphea and Causes of Scleroderma: Cytokines)

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