Scleroderma Newsroom
ISN News Manager: Jo Frowde
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Autoimmune Archive
We maintain news archives for the most recent 3 years.
2021: Jan Feb Mar
2021 - 2020 - 2019 - 2018

March 2021 Autoimmune News

Beyond bones: The relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study. Symptomatic hypermobility is particularly relevant to fibromyalgia and ME/CFS, and our findings highlight high rates of mis–/underdiagnosis. PubMed, Clin Med (Lond), 2021 Jan;21(1):53-58. (Also see Chronic Fatigue Syndrome and Fibromyalgia)

Soluble Antigen Arrays (SAgAs) Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes. SAgAs offer a novel and promising Antigen-specific immunotherapy platform superior to soluble peptides in inducing tolerance while mitigating risks of anaphylaxis for the treatment of T1D. PubMed, Diabetes, 2021 Jan 19;db200845. (Also see Research on Diabetes)

Cellular aspects of the pathogenesis of lupus nephritis. Better understanding of the pathogenesis of tubulointerstitial inflammation will identify novel therapeutic targets predicted to improve outcomes in our patients with lupus nephritis. PubMed, Curr Opin Rheumatol, 2021 Mar 1;33(2):197-204. (Also see B Cells and T Cells) and Treatments for Lupus)

Suicidal risks with psoriasis and atopic dermatitis: Systematic review and meta-analysis. The study findings support emerging evidence of increased risk of suicidal ideation and behavior with psoriasis. PubMed, J Psychosom Res, 2021 Feb;141:110347. (Also see Psoriasis and Psoriatic Arthritis and Suicide Prevention)

Anti-inflammatory diet (AID) and inflammatory bowel disease: what clinicians and patients should know? This review aimed to summarize available data from various studies to evaluate the AID diet effectiveness. PubMed, Intest Res, 02/03/2021. (Also see Bowel Dysfunction)

Targeting the endocannabinoid system with microbial interventions to improve gut integrity. This review discusses the role of the endocannabinoid system in regulating the gut barrier integrity and highlights current efforts to develop new endocannabinoid-targeted microbial interventions. PubMed, Prog Neuropsychopharmacol Biol Psychiatry, 2021 Mar 2;106:110169. (Also see Endocannabinoid System)

Acceptability and Adequacy of a Non-endoscopic Cell Collection Device for Diagnosis of Barrett's Esophagus (BE): Lessons Learned. Diagnostic characteristics suggest that non-endoscopic assessment of BE deserves further development as an alternative to endoscopy. PubMed, Dig Dis Sci, 02/03/2021. (Also see Esophageal (Throat) Involvement)

The impact of pain on the quality of life (QOL) of patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD): a multicenter cross-sectional study from Palestine. Pain has a significant negative impact on QOL in ESRD patients undergoing HD and our findings provide reliable data for educators and clinicians working with HD patients. PubMed, Health Qual Life Outcomes, 2021 Feb 2;19(1):39. (Also see Kidney (Renal) Dialysis and Transplant)

Cryopreserved human adipose-derived stromal vascular fraction (SVF) maintains fracture healing potential via angiogenesis and osteogenesis in an immunodeficient rat model. SVF cells can enhance bone healing and cryopreserved cells have almost equal potential as fresh cells. PubMed, Stem Cell Res Ther, 2021 Feb 4;12(1):110. (Also see Vascular Involvement)

Association of clinical characteristics, disease activity and health-related quality of life in systemic lupus erythematosus (SLE) patients with major depressive disorder (MDD). Predictors of MDD in SLE patients include higher scores in pain and global assessment, poor or fair self-reported health, and specific organ involvement. PubMed, Rheumatology (Oxford), 2021 Feb 6;keab123. (Also see Symptoms and Complications of Lupus and Depression)

Go to Autoimmune News: February 2021

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