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Šì¦ä§Ã¡¼÷Á¡ ±ýàÐ, ÍÁ¡÷ 150,000 Ó¾ø 500,000 «¦Áâì¸÷¸¨Ç, Ìè¢ôࡸ 30 Ó¾ø 50 ž¢üÌðàð¼ ¦àñ¸¨Çò ¾¡ìÌõ ´Õ «Ã¢Â, ¿£ñ¼¸¡ä §¿¡ö ±??ýÚ Á¾¢ôࢼôàðÎûÇÐ. ??þÐ 100,000 Áì¸Ç¢ø 30 §àÕìÌ ±?ýè Å¢¸¢¾ò¾¢öõ, ¿¡?ýÌ ¦àñ¸Ç¢ø ´Õ ¬ÏìÌ ±?ýè Å¢¸¢¾ò¾¢öõ ¿¢¸ú¸¢èÐ.
What is Scleroderma?
Scleroderma is a rare, chronic autoimmune disease which afflicts an estimated 150,000(1) to 500,000(2) Americans, primarily females who are 30 to 50 years old at onset. The overall occurrence is 30 people per 100,000 and the ratio of women to men is about four to one.
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(PDF À¢ÃÍÃõ) Šì¦Ä§Ã¡¼÷Á¡ (Šì¦Ä÷-µ-¼÷Á¡) ±ýÈ¡ø “«Øò¾Á¡É §¾¡ø” ±ýÚ ¦À¡Õû. þ󧿡ö ¸ñ¼Å÷¸ÙìÌ §¾¡ø þÚì¸õ ÁüÚõ ¾ÊôÒ, þÃò¾ ¿¡Çí¸ÙìÌ §º¾õ, þýõ ÁüÚõ §¿¡ö ±¾¢÷ôÒ «¨ÁôÀ¢ø Á¡üÈí¸û ¬¸¢Â¨Å ¿¢¸ú¸¢ýÈÉ. À¢ÃÍÃò¾¢ø, Šì¦Ä§Ã¡¼÷Á¡-Å¢ý «È¢ÌÈ¢¸¨Çô ÀüȢ ÀðÊÂø ¯ûÇÐ! º÷ŧ¾º oslash; ¯ûÇÐ! º÷ŧ¾º Šì¦Ä§Ã¡¼÷Á¡ «¨ÁôÒ
Brochures About Scleroderma
These brochures are in PDF format. The files will open automatically in Adobe Reader, which is a free program which is already installed on most computers. If you click on the file link and it doesn't open, download Adobe Reader here.
What in the world is Scleroderma? (PDF Brochure) Scleroderma (sklare-oh-derma) means "hard skin." This complex disease involves tightening and thickening of the skin, blood vessel damage, inflammation and immune system changes. Brochure includes a systemic scleroderma symptom checklist! International Scleroderma Network..
Šì¦ä§Ã¡¼÷Á¡ ±??ýàÐ ¯ñ¨Á¢ø ±?ýÉ? ??þó¾ §¸ûÅ¢ì¸¡É ?Å¢¨¼ «è¢Â, ¯Â÷¾Ã ÁÕòÐÅ ÁüÚõ ???þ¾Ã ¾¸Åø¸û «¼í¸¢Â ³.±Š.±?ý-É¢ý Šì¦ä§Ã¡¼÷Á¡Å¢?ý ÌÃø¸û òò¾¸ò ¦¾¡Ìô¨à àÊìÌÁ¡Ú àâóШà ¦ºö¸¢§è¡õ. ??þÐ §¿¡Â¡Ç¢¸û, «Å÷¸ùìÌ à½¢Â¡üڧš÷, ÁüÚõ ÁÕòÐÅ÷¸û ¬¸¢Â «¨ÉÅáöõ ´Õ§ºÃ à¡Ã¡ð¼ôàÎõ ´Õ òò¾¸ò ¦¾¡Ìôà¡Ìõ!
þó¾ô òò¾¸ò ¦¾¡Ìôò Šì¦ä§Ã¡¼÷Á¡ ÅøöÉ÷¸Ç¢??ý ¸ðΨøû, ÁüÚõ §¿¡Â¡Ç¢¸Ç¢?ý ¯ñ¨Áì ¸¨¾¸¨Ç ¯ûǼ츢ÂÐ. §¿¡Â¡Ç¢¸û ¾í¸û §¿¡Â¢??ý ¾ý¨Á àüè¢ Å¢Ç츢ì ÜÚÅм?ý, Šì¦ä§Ã¡¼÷Á¡Å¢?ý «è¢Ì袸¨Çì ¸ñ¼è¢óÐ §¿¡¨Âì ¨¸Â¡ùõ Ó¨è¸û àüè¢Â ¾í¸û ¬§ä¡º¨É¸¨ÇÔõ ย÷óÐ ¦¸¡û¸¢è¡÷¸û. À¡÷ì¸:Šì¦Ä§Ã¡¼÷Á¡ Òò¾¸ì¸¢¼íÌ.
Books About Scleroderma
But what is scleroderma really like?! To answer that, we strongly recommend the ISN's Voices of Scleroderma book series for top quality medical and support information. It receives rave reviews from patients, caregivers and doctors alike!
Articles by highly esteemed scleroderma experts are combined with true stories from patients and caregivers explaining their illness and sharing their ideas for coping with all types of scleroderma symptoms.
Šì¦ä§Ã¡¼÷Á¡ ??þÃñΠŨ¸ôàÎõ - ¯¼ä¢?ý ?´Õ Ìè¢ôà¢ð¼ à̾¢Â¢ø ÁðÎõ §¾¡?ýÚ¾ø (§ä¡ì¸¨äŠð - localized), ÁüÚõ ¯¼ä¢?ý àä à̾¢¸Ç¢ø §¾¡??ýÚ¾ø (…¢Šð¼Á¢ì - systemic).
…¢Šð¼Á¢ì(systemic) Ũ¸Â¡ÉÐ ¯¼ä¢?ý ±ó¾ô à̾¢Â¢ø §ÅñÎÁ¡É¡öõ §¾¡??ýèä¡õ (§¾¡ø, ?þÃò¾ ¿¡Çí¸û, ÁüÚõ ¯¼ä¢?ý ¯ûùÚôò¸û). ?þÐ "…¢Šð¼Á¢ì Šì¦äá…¢Š" ÁüÚõ Ê·ôäŠ(diffuse), ä¢Á¢¼ð(limited), ì¦ÃŠð(CREST) ÁüÚõ µÅ÷ä¡ô(overlap) ¬¸¢Â ¦àÂ÷¸Ç¡ø Ìè¢ì¸ôàθ¢èÐ.
§ä¡ì¸¨äŠð Ũ¸Â¡ÉÐ Á¡÷·à¢Â¡(morphea) ÁüÚõ ä£É¢Â÷(linear) ±ÉôàÎõ, ?þÐ ¯¼ä¢?ý §¾¡ø (ÁüÚõ «¾??ý «Ê¢ø «¨Áó¾¢ÕìÌõ ¾¢Íì¸û) à̾¢Â¢ø ²üàÎõ; ¬É¡ø þ¾É¡ø ¯¼ä¢?ý ¯ûùÚôò¸ùìÌ à¡¾¢ô§à¡, «øäÐ ?´ÕÅÃÐ ¬Ôð¸¡äõ ̨èŧ¾¡ ²ü༡Ð.
̨Æó¾¸ùìÌ ²üàÎõ Šì¦ä§Ã¡¼÷Á¡ ÌÆó¨¾ôàÕÅ Šì¦ä§Ã¡¼÷Á¡ ±Éôàθ¢èÐ.
Å¢Çì¸í¸û «è¢Â, Šì¦ä§Ã¡¼÷Á¡-Å¢??ý Ũ¸¸û àì¸ò¨¾ô à¡÷ì¸×õ.
Types of Scleroderma
There are two main types of scleroderma, localized and systemic.
The systemic forms can affect any part of the body (skin, blood vessels, and internal organs.) The systemic forms are also referred to as "systemic sclerosis" plus other terms such as diffuse, limited, CREST, and overlap.
The localized forms are morphea and linear. They affect only the skin (and sometimes the underlying tissues) but do not affect the internal organs, or reduce one's life expectancy in any way.
When any form of scleroderma (either localized or systemic) occurs in children, it is also called Childhood Scleroderma or Juvenile Scleroderma.
See Types of Scleroderma page for further explanation.
Šì¦Ä§Ã¡¼÷Á¡ ´Õ «Ã¢Â §¿¡Â¡¸×õ, ¦ÅÌ º¢Ä ÁÕòÐÅ÷¸Ù째 ÀâîºÂÁ¡É §¿¡Â¡¸×õ þÕôÀ¾¡ø, þ¾¨Éì ¸ñ¼È¢Â ¿£ñ¼ ¸¡ÄÁ¡Åмý, ¸ÊÉÁ¡¸×õ þÕ츢ÈÐ. ¬ÃõÀ ¸ð¼í¸Ç¢ø þÐ ãðÎÅÄ¢ (¬÷ò¨ÃðÊŠ) §À¡ýÈ º¢Ä þ¨½ôÒò ¾¢Í §¿¡ö¸¨Ç ´ò¾¢Õ츢ÈÐ.
¦ÀÕõÀ¡Öõ, §¿¡¨Âì ¸ñ¼È¢Å¾¢ø ¯ûÇ ¿¢îºÂÁ¢ý¨ÁÔõ, ²Á¡üÈÓõ ÁÉ¿¢¨Ä¨Â ¦ÅÌÅ¡¸ À¡¾¢ôÀ¾¡ø, §¿¡¨Â °÷ƒ¢¾ôÀÎò¾¢ì ¦¸¡ûžüÌû «Å÷¸ÙìÌ ²üÀÎõ ÅÕò¾í¸§Ç þ󧿡¢ý ÐÂÃÁ¡É ¸ð¼õ ±ý¸¢È¡÷¸û þ󧿡¡Ǣ¸û.(4)
§¿¡¨Â ¿¢÷½Â¢ôÀ¾¢ø ¯ûÇ þ¼÷À¡Î¸û - À̾¢¨Âô À¡÷ì¸×õ.
Difficult Diagnosis
Proper diagnosis of scleroderma is often long and difficult, since it is a rare disease which few doctors are well-versed in, and in the early stages it may resemble many other connective tissue diseases, such as systemic lupus erythematosus, polymyositis, and rheumatoid arthritis, just to name a few.
Often the diagnostic uncertainty and frustration takes a huge toll on the psychological well-being of these patients, who describe their journey to diagnosis as being by far the most difficult part of their illness.(4) See Difficult Diagnosis.
Effects of Systemic Scleroderma
…¢Šð¼Á¢ì Šì¦Ä§Ã¡¼÷Á¡ §¾¡Ä¢Öõ,¯¼Ä¢ý ¯ûÙÚôҸǢÖõ ¯ûÇ ¾¢Íì¸Ç¢ø ÅÄ¢Ôõ Å£ì¸Óõ(fibrosis) ²üÀÎòи¢ÈÐ. þ¾ý Å¢¨ÇÅ¡¸ À¡¾¢ì¸ôÀð¼ §¾¡Öõ, ¯¼ø ¯ÚôÒõ þÚ¸¢ì ¸¡½ôÀΞ¡ø, þ󧿡ö “ÁÉ¢¾÷¸¨Çì ¸øÄ¡¸ Á¡üÚõ §¿¡ö” ±ýÚ ÀÃÅÄ¡¸ «È¢ÂôÀθ¢ÈÐ.
Effects of Systemic Scleroderma
The systemic forms of scleroderma cause fibrosis (scar tissue) to be formed in the skin and/or internal organs. The fibrosis eventually causes the involved skin or organs to harden, which is why scleroderma is popularly known as the "disease that turns people into stone."
Šì¦Ä§Ã¡¼÷Á¡ §¿¡ö ²üÀΞü¸¡É ãÄ측ýí¸û þýÛõ ¸ñ¼È¢ÂôÀ¼Å¢ø¨Ä. º¢Ä Ũ¸Â¡É §¿¡öìÌ Ã…¡ÂÉò ¾¡ì̾ø¸û ¸¡Ã½Á¡¸ þÕì¸Ä¡õ ±ýÚ ¿õÀôÀθ¢ÈÐ. ÁÃÀÏì¸û ÁüÚõ º¢Ä ¨ÅÊ ¸¢ÕÁ¢¸û ¬¸¢Â¨ÅÔõ ¸¡Ã½Á¡¸ «¨ÁÂÄ¡õ ±ýÚõ ¸Õ¾ôÀθ¢ÈÐ. Šì¦Ä§Ã¡¼÷Á¡-Å¢ý ãÄ측ýí¸û- À̾¢¨Âô À¡÷ì¸×õ.
Causes of Scleroderma
The cause of scleroderma is unknown. Some cases of scleroderma have been linked to chemical exposures. Genetics, fetal cells, and viruses might also be factors in the development of scleroderma. See Causes of Scleroderma.
Šì¦Ä§Ã¡¼÷Á¡ ´Õ ¦¾¡üÚ§¿¡ö(1) «øÄ, «¾¡ÅÐ, þÐ ¨¸ÌÖìÌžý ãÄÁ¡¸§Å¡, ¸ðÊôÀ¢ÊôÀ¾ý ãÄÁ¡¸§Å¡, Óò¾Á¢Îžý ãÄÁ¡¸§Å¡, ¯¼ÖÈ× ¦¸¡ûžý ãÄÁ¡¸§Å¡, þÃò¾ ºõÀó¾Á¡¸§Å¡, §¿¡Â¡Ç¢ ¯ñÀ¾üÌô ÀÂýÀÎò¾¢Â À¡ò¾¢Ãí¸¨Çô ÀÂýÀÎòО¡§Ä¡, «øÄÐ ¸¡üÚ Å¡Â¢Ä¡¸ þÕÁø, ÐõÁø ãÄÁ¡¸§Å¡ ²üÀΞ¢ø¨Ä. þ󧿡ö ÒüÚ§¿¡ö ¯ñ¼¡ì¸ìÜÊÂÐõ «øÄ.
Scleroderma is Not Contagious or Cancerous
Scleroderma is not classified as contagious (1), which means that you cannot get scleroderma by shaking hands, hugging, kissing, sexual contact, contact with blood or bodily fluids, sharing eating utensils, or by airborne contact from coughing or sneezing. And it is not cancerous in any way.(1)
þý¨È ¸¡Ä¸ð¼ò¾¢ø, Šì¦Ä§Ã¡¼÷Á¡ §¿¡¨Â ̽ôÀÎòОü¸¡É ÁÕóи§Ç¡, º¢¸¢î¨º Өȸ§Ç¡ þø¨Ä. ¬É¡ø,þ󧿡¢ý «È¢ÌÈ¢¸¨Ç ̽ôÀÎòОü¸¡É º¢Èó¾ º¢¸¢î¨º Өȸû ÀÄ ¯ûÇÉ. þó¾ ŨÄò¾Çò¾¢ø ÌÈ¢ôÀ¢¼ôÀðÊÕìÌõ §¿¡Â¢ý «È¢ÌÈ¢¸Ç¢ø ÀÄ, …¢Šð¼Á¢ì(systemic) Šì¦Ä§Ã¡¼÷Á¡-Å¢ý «È¢ÌÈ¢¸û ¬Ìõ. …¢Šð¼Á¢ì Šì¦Ä§Ã¡¼÷Á¡Å¢ ý «È¢ÌÈ¢¸ûÁüÚõ ÁÕòÐÅ ¬Ã¡ö¸û À̾¢¨Âô À¡÷ì¸×õ. “Šì¦Ä§Ã¡¼÷Á¡ ±ýÈ¡ø ±ýÉ?” ±ýÈ À¢ÃÍÃò¾¢ÖûÇ, …¢Šð¼Á¢ì Šì¦Ä§Ã¡¼÷Á¡Å¢ý «È¢ÌÈ¢¸Ç¢ý ÀðʨÄô À¡÷ì¸×õ. þÐ PDF-ÅÊÅò¾¢ø ¯ûÇÐ.
…¢Šð¼Á¢ì Šì¦Ä§Ã¡¼÷Á¡Å¢ ý «È¢ÌÈ¢¸û ÁüÚõ ÁÕòÐÅ ¬Ã¡ö¸û À̾¢¨Âô À¡÷ì¸×õ.
Scleroderma Symptoms and Treatments
At present, there are no proven treatments or cure for any forms of scleroderma. However, there are effective therapies for many of the symptoms. Most of the symptoms listed in this website are those of systemic scleroderma. See Systemic Scleroderma Symptoms and Scleroderma Treatments and Clinical Trials. Also see the Systemic Scleroderma Symptom Checklist in our free PDF from the ISN's "What is Scleroderma?" brochure.
Šì¦Ä§Ã¡¼÷Á¡-Å¢ý º¢¸¢î¨ºì¸¡É À⧺¡¾¨É¸û º¢Ä, ¿õÀ¢ì¨¸äðÎõ Ũ¸Â¢ø «¨ÁóÐûÇÉ. þÅüÚû ‘Š¦¼õ ¦ºø Á¡üÚ Ó¨È(BMT)’-Ôõ «¼íÌõ.À⧺¡¾¨É¸û - À̾¢¨Âô À¡÷ì¸×õ.
Scleroderma Clinical Trials
There are some experimental therapies which show promise for treatment of scleroderma, including Stem Cell Transfusion (BMT). See Clinical Trials.
Šì¦Ä§Ã¡¼÷Á¡-¨Åô ÀüȢ À¢ÃÍÃõ NIAMS
Šì¦Ä§Ã¡¼÷Á¡ - ´Õ ¸ñ§½¡ð¼õ MayoClinic.com
Šì¦Ä§Ã¡¼÷Á¡-Å¢ý ÌÃø¸û - À̾¢ 1 þó¾ô Òò¾¸õ Šì¦Ä§Ã¡¼÷Á¡-¨Åô ÀüÈ¢ ÅøÖÉ÷¸û ÜÚõ ÁÕòÐÅò ¾¸Åø¸¨Ç «¼ì¸¢ÔûÇÐ. þ¾¢ø Šì¦Ä§Ã¡¼÷Á¡-Å¢ý «È¢ÌÈ¢¸Ç¢ý ÀðÊÂÖõ, þ󧿡¡ø À¡¾¢ì¸ôÀð¼ 100 §¿¡Â¡Ç¢¸Ç¢ý ¸¨¾¸Ùõ «¼íÌõ. º÷ŧ¾º Šì¦Ä§Ã¡¼÷Á¡ «¨ÁôÒ
Šì¦Ä§Ã¡¼÷Á¡ ±ýÈ¡ø ±ýÉ? “¯í¸û ¯¼Ä¢ý º¢Ä À̾¢¸Ç¢ø, §¾¡ø ¾ÊòÐ, þÚ¸¢ô §À¡Â¢Õó¾¡ø ±ôÀÊ þÕìÌõ ±ýÚ ¦¸¡ïºõ ¸üÀ¨É ¦ºöÐ À¡Õí¸û. §ÁÖõ, ÌÇ¢÷ ¾¡í¸ ÓÊ¡¾¢Õò¾ø, «Êì¸Ê ²üÀÎõ ¦¿ï¦ºÃ¢îºø, ãðÎ þÚ̾ø, ÁüÚõ À¢È ¯ûÙÚôÒ À¢ÃîºÉ¨¸û ¬¸¢Â¨ÅÔõ þÕó¾¡ø?”. ²Á¢ (´Õ …¢Šð¼Á¢ì Šì¦Äá…¢Š §¿¡Â¡Ç¢Â¢ý Á¸û)
Šì¦Ä§Ã¡¼÷Á¡ ±ýÈ¡ø ±ýÉ? ãðÎÅÄ¢ «¨ÁôÒ («¦Áâ측)
Šì¦Ä§Ã¡¼÷Á¡ ±ýÈ¡ø ±ýÉ? ¦ÁÊ…¢ý¦¿ð
Information about Scleroderma
Handout on Health: Scleroderma NIAMS
Overview of Scleroderma MayoClinic.com
Voices of Scleroderma Volume 1 Book offers medical information about scleroderma by leading experts. Includes scleroderma symptom checklist, plus 100 personal stories of people living with scleroderma and related illnesses. International Scleroderma Network
What is Scleroderma? "Imagine for me if you would that in certain areas of your body the skin has begun to thicken and harden. Then on top of this, you have a painful sensitivity to cold, frequent heartburn, stiff joints and various other internal problems." Amy (Daughter of a Systemic Sclerosis patient)
What is Scleroderma? MedicineNet
…¢Šð¼Á¢ì Šì¦Ä§Ã¡¼÷Á¡
§Ä¡¸¨ÄŠð Šì¦Ä§Ã¡¼÷Á¡
Scleroderma Patient Stories
Systemic Scleroderma:
Localized Scleroderma:
Others
Related Links: India
Banumathy Sridharan: ISN Tamil Translator
ISN: Kannada by Kishori Mundargi
ISN: Tamil by Banumathy Sridharan
Aziz: Surviving Son of Gangrene Patient (India) What I am writing now is something even more horrible than what you might have read in a Stephen King's scariest of novels. My father died of gangrene…
Jonty: Son of Scleroderma Patient (Hyderabad, India) In 1997, I secured a seat in a medical college in Hyderabad and enrolled for the MBBS degree course. I then took my mother to meet Dr. Narasimhalu…
Kamlesh: Husband of Limited Scleroderma Patient (India) In a pulmonary function test, there was severe restriction and severe obstruction…
Kishori Mundargi, Kannada Translator
Madhu Bhatia: Morphea (Delhi, India) When will I get respite and correct diagnosis? Pain on the wound is excruciating. I am entangled in a web of doctors with no clear diagnosis…
Mani: Son of Systemic Scleroderma Patient (Hyderabad, India) My mother was always complaining of breathlessness, slight fever, and nails and fingers turning blue when exposed to cold air…
Pushpa: Scleroderma with Raynaud's (Bangalore, India) Around my 21st winter, the year of 1982 in Calcutta, India, is when I first noticed my nails and fingers were turning blue when exposed to the cold…
Seema: Progressive Systemic Sclerosis (India) Finally I came to know about Dr. V.R. Joshi, an internist who specialized in rheumatic diseases…
Sujatha: Diffuse Systemic Sclerosis (Bangalore, India) I am 36 years old and hail from Bangalore in the Southern State of Karnataka in India…
SCLERO.ORG is the world's leading nonprofit for trustworthy research, support, education and awareness for scleroderma and related illnesses. We are a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team. Donations may also be mailed to:
7455 France Ave So #266
Edina, MN 55435-4702 USA