Scleroderma Newsroom
Janey Willis, ISN News GuideHello, I am Janey Willis, ISN News Manager and ISN Asst. Webmaster. David Becker, ISN Assistant News Guide researches our Autoimmune News section. Jeannie McClelland, ISN Assistant News Guide, researches Scleroderma Medical and Media News. Assistant News Guides Lisa Bulman and Judy Tarro post these stories to our Sclero Forums. Stephen Dickson prepares our RSS Newsfeed.
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January 2008
Assessment of Pulmonary Arterial Hypertension in Patients with Systemic Sclerosis: Comparison of Noninvasive Tests with Results of Right-Heart Catheterization (RHC). Echo appeared to be the most useful among the noninvasive tests. However, due to the low sensitivity of noninvasive testing, RHC should remain the gold standard. (PubMed) J Rheumatol. 2008 Jan 15. (Also see: PAH )
Evaluation of cardiac abnormalities by Doppler echocardiography in a large nationwide multicentric cohort of patients with systemic sclerosis (SSc). Left and right heart diseases, including Pulmonary Arterieal Hypertension, Left Ventricle hypertrophy and diastolic dysfunction, are common in SSc. (PubMed) Ann Rheum Dis. 2008 Jan;67(1):31-6. (Also see: Cardiac )
Home parenteral nutrition (HPN): an effective and safe long-term therapy for systemic sclerosis-related intestinal failure. Although patient numbers were small, our findings suggest that HPN can be safely and successfully used long-term in patients with SSc. Rheumatology 2008 47(2):176-179. (Also see: GI )
Biofeedback Helps Alleviate Raynaud's Disease Symptoms. Biofeedback is a mind-body technique using electronic instruments to help individuals gain awareness and control over their body and mind. Medical News Today. 01/12/08. (Also see: Raynaud's )
Stem cell transplantation has long-term benefits in systemic sclerosis. Autologous hematopoietic stem cell transplantation improves survival and reduces skin thickening and other symptoms of systemic sclerosis. TheJobCure (Reuters) 01/09/08. (Also see: Clinical Trials )
Effect of Mycophenolate Mofetil (MMF) on Pulmonary Function in Scleroderma-Associated Interstitial Lung Disease (SSc-ILD). These retrospective data suggest MMF improves vital capacity (VC) in patients with SSc-ILD. (PubMed) Chest. 2007 Dec 10. (Also see: Cellcept and Pulmonary Fibrosis )
Cardiac abnormalities common in systemic sclerosis. Left and right heart diseases, including pulmonary arterial hypertension (PAH), left ventricular hypertrophy, and diastolic dysfunction, are frequently found in patients with systemic sclerosis. The Job Cure. (Reuters) 01/01/08. (Also see: Cardiac )
Molecular Pathway Appears Crucial In Development Of Pulmonary Fibrosis.The investigators found that a specific molecular pathway appears responsible for key aspects of the scarring of lung tissue that characterizes Idiopathic Pulmonary Fibrosis. Medical News Today. 12/16/07. (Also see: Pulmonary Fibrosis )
Increased Serum Interleukin 23 in Patients with Systemic Sclerosis. The results suggest that IL-23 is associated with induction of SSc and that blockade of IL-23 can be a potential therapeutic strategy in early SSc. Journal of Rheumatology. Vol 35: No 1. Jan 2008. (Also see: Causes of SSc: Interleukins )
Natural History of Ischemic Digital Ulcers (DU) in Systemic Sclerosis: Single-Center Retrospective Longitudinal Study. Development of DU typically occurred within 5 years of the first non-Raynaud clinical symptom of SSc in the majority of patients. J Rheumatol 2007;34:2423-30. (Also see: Digital Ulcers )
Onset and enhancement of systemic sclerosis after treatments for multiple sclerosis. This case report shows that some form of treatment useful for MS might enhance the manifestations of SSc. (PubMed) Rheumatol Int. 2007 Dec 8. (Also see: Causes: Medications )
A new method allows for the early diagnosis of pulmonary hypertension. The great advantage of this system, which is based on the ultrasound technique, is that it allows specialists to measure the pulmonary artery systolic pressure so that pulmonary hypertension (PH) can be diagnosed earlier. EurekAlert! 11/13/07. (Also see: PH )
Cardiac Magnetic Resonance Imaging Detects Subclinical Right Ventricular Impairment in Systemic Sclerosis. Compromised right ventricular failure was found in patients with asymptomatic SSc. J Rheumatol 2007;34:2431-7. (Also see: Cardiac )
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