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janeywillisHello, I am Janey Willis, ISN News Director and ISN Asst. Webmaster. David Becker, ISN Assistant News Guide researches our Autoimmune News section. Jeannie McClelland, ISN Assistant News Guide, researches Scleroderma Medical and Media News. Assistant News Guide Lisa Bulman posts these stories to our Sclero Forums.
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February 2008
A regular dip could benefit fibromyalgia sufferers. Patients suffering from fibromyalgia could benefit significantly from regular exercise in a heated swimming pool. EurekAlert! 02/21/08. (Also see: Fibromyalgia )
Safer and more effective way to treat Crohn's disease. This alternative strategy, called “top-down” therapy, employs early use of immune-suppressing drugs combined with an antibody in order to address the disease from the start. Symptom-treating steroids may never even be needed. EurekAlert! 02/21/08. (Also see: Crohn's )
Clinical Trials: Fibromyalgia. A list of current and new clinical trials in the United States on Fibromyolgia. Center Watch. 02/15/08. (Also see: Fibromyalgia )
Ultrasonography of Salivary Glands. A Highly Specific Imaging Procedure for Diagnosis of Sjögren's Syndrome. The data indicate that ultrasonography of major salivary glands is a noninvasive imaging procedure with high diagnostic value for the diagnosis of primary and secondary SS. J Rheumatol 2008;35:285-93. (Also see: Sjogren's Syndrome )
Association of autoantibodies with Ku and DNA repair proteins in connective tissue diseases. The presence of autoantibodies directed against macromolecular complexes known to play roles in the DNA damage response provides evidence that B-cell responses to latent or persistent DNA damage may be present at the onset or during the development of autoimmunity in certain systemic autoimmune rheumatic diseases. Rheumatology 2008 47(2):165-171. (Also see: Causes: B-cells )
Medical Edge: Accurate diagnosis relies on second test. Antiphospholipid syndrome (APS) can be diagnosed with a blood test repeated 6-12 weeks apart to compare results. PostBulletin 02/08/08. (Also see: APS )
Antiphospholipid antibody syndrome and autoimmune diseases. Evidence is growing that antiphospholipid antibodies may have a pathogenic role in pulmonary hypertension and accelerated atherosclerosis of autoimmune diseases. (PubMed) Hematol Oncol Clin North Am. 2008 Feb; 22(1):53-65. (Also see: Antibodies, Lupus, PH,and Cardiac )
High-Resolution Computed Tomography Characterization of Interstitial Lung Diseases (ILD) in Polymyositis/dermatomyositis (PM/DM). The prognosis of ILD associated with DM differs from that with PM. Mortality rates were 12% and 44% for ILD associated with PM and DM, respectively. J Rheumatol 2008;35:260-9. (Also see: PM/DM )
Evaluation of Paraoxonase Activity in Patients with Mixed Connective Tissue Disease (MCTD). Our results indicate that in patients with MCTD there is an increased risk for atherosclerosis. J Rheumatol 2008;35:237-43. (Also see: MCTD and Cardiac ) (NOTE: The antioxidant paraoxonase (PON1) is an endogenous free radical scavenger in the human body.)
 
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