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Eye Involvement
ISN Guide to Eye Involvement: Dr. Liz Irvin
Dr. Liz IrvinHello, I am Dr. Liz Irvin, your ISN Guide to Eye Involvement. In addition to helping Dr. C. Stephen Foster develop resources for this section of the ISN website, I am happy to try to respond to questions that you may have or to redirect you to resources that may be helpful. Email liz-irvin@sclero.org.
Scleroderma Eye Involvement
Normal Tension Glaucoma (NTG)
Autoimmune Iritis or Uveitis
Optic Neuropathy
Other Eye Diseases of Scleroderma
Eye Involvement in Rheumatic Diseases
Support for Eye Disease
Personal Stories
Media Stories
These symptoms may sometimes occur in systemic sclerosis (scleroderma). Scleroderma (SD) affects everyone differently. Just because something is listed here does not mean it is caused by scleroderma nor that an individual scleroderma patient will ever experience it. See Disclaimer.
Eye Involvement of Rheumatic Diseases
Eye Involvement of Rheumatic Diseases - Overview
LASIK (Laser Surgery) in Autoimmune Disease
Dry Eyes
Eye Involvement of Rheumatic Diseases - Overview
Ophthalmological involvement in rheumatic disease. The main conclusion of our study is that rheumatic patients need to be referred to an ophthalmologist for the diagnosis and the optimal treatment of ocular involvement. PubMed. Oftalmologia. 2006;50(2):56-61.
Vascular Retinopathy
Therapy insight: The recognition and treatment of retinal manifestations of systemic vasculitis. A variety of retinal signs can occur in patients who have systemic vasculitides, or who experience complications of these diseases or their treatment. Although treatment of these retinal manifestations is usually the treatment of the systemic disease, specific treatment is occasionally indicated to preserve vision. PubMed. Nat Clin Pract Rheumatol. 2006 Aug;2(8):443-51. (Also see: Vasculitis)
Proliferative vascular retinopathy in polymyositis and dermatomyositis with scleroderma (overlap syndrome). Retinal vascular occlusion with development of proliferative changes can occur in polymyositis/dermatomyositis. PubMed. Ocul Immunol Inflamm. 2007 Jan-Feb;15(1):45-9. (Also see: Polymyositis/Dermatomyositis)
LASIK (Laser Eye Surgery) in Autoimmune Diseases
Laser in situ keratomileusis (LASIK) in patients with autoimmune diseases. Laser in situ keratomileusis may be a reasonable option in patients with well-controlled or inactive autoimmune disease. PubMed. J Cataract Refract Surg. 2006 Aug;32(8):1292-5.
LASIK in Patients with Rheumatic Diseases A Pilot Study. In this small series, we found good outcomes when correcting refractive errors using LASIK in selected patients with controlled rheumatic diseases. In this series, a favorable postoperative visual outcome was obtained with no operative or postoperative vision-threatening complications. PubMed. Ophthalmology. 2005 Sep 14.
Dry Eyes
Eyes That Water Easily May Actually be Caused by Eye Dryness. There's a host of other factors that can contribute to dry eyes. LASIK surgery, and some underlying medical conditions such as diabetes, rheumatoid arthritis, scleroderma, Sjogren's syndrome and vitamin A deficiency can cause dry eyes. Medical Edge from Mayo Clinic (The Morning Call) 10/2/09.
Antibody Protein Array Analysis of the Tear Film Cytokines. Preliminary results using tears collected from patients with Sjogren's syndrome reveal methodological advantages of protein array technology and support the concept that autoimmune-mediated dry eye disease has an inflammatory component. Li, Shimin PhD. Optometry & Vision Science. August 2008. (Also see: Sjögren's)
Electrophoretic Diagnosis Of Ocular Involvement In Scleroderma Patients. Two-dimensional electrophoretic analysis of tear protein patterns of patients with scleroderma is a fast, reproducible and simple method that provides information for the diagnosis of keratoconjunctivitis sicca in these patients. V. Cojocaru AB0553-AHP EULAR 2008.
Modification of Lacrimal Film in Patients with Rheumatoid Arthritis (RA) Treated with Etanercept. Etanercept improved ocular dryness in patients with RA and dry eyes without secondary Sjogren's Syndrome (SS). As previous studies have failed to demonstrate any effect of this drug in SS it is possible to hypotesize that the physiopathologic mechanism of dry eye is different in SS patients and non-SS patients. F. Ceccarelli. [THU0217] EULAR 2006.
Prevalence of sicca symptoms in a South Australian cohort with systemic sclerosis(SSc).Out of 193 SSc patients, sicca symptoms (primarily dry eye) were present in 59% of patients with limited SSc, 49% of patients with diffuse SSc and 40% of patients with the overlap syndrome.This study confirmed that sicca symptoms are found in a high proportion of patients with SSc. Swaminathan S. (PubMed) Intern Med J. 2008 Apr 14.
 
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