| Eye Involvement |
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| These symptoms may sometimes occur in systemic sclerosis (scleroderma). Scleroderma (SD) affects everyone differently. Just because something is listed here does not mean it is caused by scleroderma nor that an individual scleroderma patient will ever experience it. See Disclaimer |
| Autoimmune Uveitis and Iritis (Eye Inflammation) |
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| Autoimmune Uveitis and Iritis (Eye Inflammation) Overview |
| When inflammation affects the eyes, it is called different things depending on which part of the eye it affects (the iris or the uvea). |
| Uveitis. Uveitis is inflammation of the uvea, which is the vascular layer of the eye sandwiched between the retina and the white of the eye (sclera). The uvea extends toward the front of the eye and consists of the iris, choroid layer and ciliary body. The most common type of uveitis is an inflammation of the iris called iritis (anterior uveitis). MayoClinic. |
| Prevalence of the Spondyloarthritides in Patients with Uveitis. Uveitis is associated not only with AS and reactive arthritis, but also with undifferentiated spondyloarthritis and psoriatic arthritis. J Rheumatol. November 2004;31:2226-9. |
| Type I collagen is the autoantigen in experimental autoimmune anterior uveitis. Although human anterior uveitis has been historically characterized as a collagen disease, this is first time collagen has been directly identified as the target autoantigen in uveitis. PubMed. J Immunol. 2004 Jun 1;172(11):7086-94. |
| Help for inflammatory eye disease. Inflammatory Eye Diseases (the most common being scleritis and uveitis) are the fifth-leading cause of blindness in the United States. Prednisone is the common treatment. Now, CellCept—a drug used to prevent organ transplant rejection—can treat eye inflammation and get patients on lower doses of, or even off, prednisone. Ivanhoe Broadcast News 02-20-06. |
| Causes of Uveitis |
| What causes Uveitis? Uveitis has many potential causes, including infection with a virus, fungus, bacteria or parasite, inflammatory disease affecting other parts of the body, or injury to the eye. MedicineNet.com |
| Granulomatous uveitis, CREST syndrome, and primary biliary cirrhosis. Our case report illustrates an association between ocular and hepatic diseases, which may be entirely coincidental but could, nevertheless, encourage further investigation for a common immunological pathway. Br J Ophthalmol 2000;84:546. (Also see: CREST Syndrome and Liver Involvement) |
| Symptoms of Uveitis |
| Symptoms of Uveitis. Lists of signs, symptoms and characteristics of uveitis. MayoClinic. |
| Uveitis in the internist's office: are a patient's eye symptoms serious? If the diagnosis of uveitis is made, internists must search for an underlying cause, such as infection or an autoimmune disease. PubMed. Cleve Clin J Med. 2005 Apr;72(4):329-39. |
| Treatments of Uveitis |
| Treatments and Drugs. If uveitis is caused by an underlying condition, treatment will focus on treating that specific condition. The goal of treatment is to reduce the inflammation in your eye. MayoClinic. |
| Effect of sex hormones on experimental autoimmune uveoretinitis (EAU). The data support the hypothesis that sex hormones may affect autoimmune diseases by inducing changes in the cytokine balance. This suggests that sex hormone therapy could be considered as an adjunct to anti-inflammatory agents to treat ocular autoimmune diseases in humans. PubMed. Immunol Invest. 2003 Nov;32(4):259-73. |
| Sulfasalazine Reduces the Number of Flares of Acute Anterior Uveitis Over a One-Year Period. The mean number of flares in the pre-SSZ year was 3.4, which was significantly reduced to 0.9 in the year of treatment. J Rheumatol NO. 6 JUNE 2003;30:1277-9. |
Hello, I am Dr. Liz Irvin, your ISN Guide to Eye Involvement.