| Eye Involvement |
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| These symptoms may sometimes occur in systemic sclerosis (scleroderma). Scleroderma (SD) affects everyone differently. Just because something is listed here does not mean it is caused by scleroderma nor that an individual scleroderma patient will ever experience it. See Disclaimer. |
| Eye Involvement in Scleroderma (Systemic Sclerosis) |
| Eye symptoms and diseases that may be related to scleroderma include Normal Tension Glaucoma, Autoimmune Iritis or Uveitis, and types of Optic Neuropathy. |
| Ocular Inflammatory Disease |
| A Patient Guide to Ocular Inflammatory Disease. This is an online guide, covering symptoms, diagnosis and treatment for inflammatory eye diseases. In addition, printed copies of this guide can be requested free of charge from the Ocular Immunology and Uveitis Foundation. (Also see: Dr. C. Stephen Foster, ISN Medical Advisory Board) |
| Normal Tension Glaucoma (NTG) |
| Normal-Tension Glaucoma. Normal-tension glaucoma (also called low-tension glaucoma) is a unique condition in which optic nerve damage and vision loss have occurred despite a normal pressure inside the eye. Although its cause is not completely understood, normal-tension glaucoma is generally believed to occur either because of an unusually fragile optic nerve that can be damaged despite a normal pressure inside the eye or because of reduced blood flow to the optic nerve. WebMD. |
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| Autoimmune Iritis or Uveitis (Eye Inflammation) |
| Autoimmune Iritis or Uveitis. When inflammation affects the eyes, it is called different things depending on which part of the eye it affects (the iris or the uvea). ISN. |
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| Optic Neuropathy |
| Optic Neuropathy is a general term used for damage to the optic nerve regardless of the cause of the damage. Specific types of optic neuropathy can be identified when the cause of the damage is known. For example, regular glaucoma is caused by high pressure inside the eye and anterior ischemic optic neuropathy is caused by problems with the blood supply to the optic nerve. ISN. |
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| Other Eye Diseases of Scleroderma |
| Pellucid Marginal Degeneration and Systemic Sclerosis (Scleroderma) |
Pellucid marginal degeneration and scleroderma. Pellucid marginal degeneration is characterised by non-inflammatory and progressive peripheral corneal thinning inferiorly, often with high against-the-rule astigmatism. We report a case of a 55-year-old woman with systemic scleroderma who presented with rapidly progressing against-the-rule astigmatism. PubMed. Clin Exp Optom. 2004 May;87(3):180-4. |
| Pyoderma Gangrenosum and Systemic Sclerosis (Scleroderma) |
| Sclerokeratitis and facial skin lesions: a case report of pyoderma gangrenosum and its response to dapsone therapy. Pyoderma gangrenosum is a rare autoimmune disorder that can affect the eye. Biopsy of affected tissue is the key to diagnosis. Immunomodulating therapy can be a useful adjunct to the traditional steroid therapy. PubMed. Cornea 2007 Feb;26(2):215-9. |
| Retinopathy and Systemic Sclerosis (Scleroderma) |
| Proliferative vascular retinopathy in polymyositis and dermatomyositis with scleroderma (overlap syndrome). Retinal vascular occlusion with development of proliferative changes can occur in polymyositis/dermatomyositis. PubMed. Ocul Immunol Inflamm. 2007 Jan-Feb;15(1):45-9. (Also see: Overlap Syndrome and Polymyositis/Dermatomyositis) |
| Retinal Manifestations of Systemic Vasculitis. Retinal signs in scleroderma are rare and usually secondary to hypertension, although it has been noted that the signs are often more florid than might be expected for the level of blood pressure. Evaluation of the retinal vasculature can therefore furnish clues to the state of the patient''s systemic vasculitis. M.R. Stanford Medical eye unit, St thomas hospital, london, United Kingdom. [SP0129] EULAR 2005. |
| Investigations for retinopathy in an avian model for systemic sclerosis. Our data raise serious doubts about primary posterior ocular involvement in human SSc. However, fundal examinations in patients with SSc may have their justification for assessment of hypertensive retinopathy. PubMed. Exp Eye Res. 2004 Jul;79(1):85-92. |
| Retinal findings in systemic sclerosis: a comparison with nailfold capillaroscopic patterns. Retinal abnormalities are often seen in patients with SSc and they may reflect the vascular changes characteristic of SSc. Ann Rheum Dis. 2003 Mar;62(3):204-7. |
| Eye Involvement of Rheumatic Diseases |
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| Support for Eye Diseases |
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Hello, I am Dr. Liz Irvin, your ISN Guide to Eye Involvement.