| Associated Conditions: MAIN MENU | |
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| Fibromyalgia (FMS) |
| This page was written by Shelley Ensz and has not yet been medically edited. These illnesses affect everyone differently. Just because something is listed here does not mean an individual patient will ever experience it. See Disclaimer. |
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| Treatments for Fibromyalgia (FMS) |
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| Overview of Treatments for FMS |
| Clinical Trials: Fibromyalgia. A list of current and new clinical trials in the United States on Fibromyolgia. Center Watch. 02/15/08. |
| The high frequency of manic symptoms in fibromyalgia does influence the choice of treatment? Subjects with FM showed an higher comorbidity with Generalised Anxiety Disorder, Panic Disorder and Major Depressive Disorder than controls. Clinical Practice and Epidemiology in Mental Health 2006, 2:36 doi:10.1186/1745-0179-2-36. |
| Use of complementary and alternative medicine (CAM) providers by fibromyalgia patients under insurance coverage. With insurance coverage, a majority of patients with FMS will visit CAM providers. The sickest patients use more CAM, leading to an increased number of health care visits. Wiley Interscience 03/30/07. Arthritis Care and Research, Volume 57, Issue 1, Pages 71 - 76. |
| Alternative Therapies |
| Influence of Craniosacral Therapy on Anxiety, Depression and Quality of Life in Patients with Fibromyalgia (FM). The present study shows that craniosacral therapy improves the quality of life of patients with FM, reducing their perception of pain and fatigue and improving their night rest and mood, with an increase in physical function. Our craniosacral therapy protocol also reduces anxiety levels, partially improving the depressive state. G. A. Matarán-Peñarrocha. eCAM Advance Access. September 3 2009. |
| Chiropractic treatment for fibromyalgia: a systematic review. Currently, there is insufficient evidence to conclude that chiropractic is an effective treatment for fibromyalgia. Edzard Ernst. (SpringerLink) Clinical Rheumatology June 22, 2009. |
| Efficacy of hydrotherapy in fibromyalgia syndrome (FMS)—a meta-analysis of randomized controlled clinical trials. There is moderate evidence that hydrotherapy has short-term beneficial effects on pain and HRQOL in FMS patients. J. Langhorst. Rheumatology Advance Access. July 16 2009. |
| Cognitive Behavioral Therapy (CBT) for the Treatment of Fibromyalgia Syndrome: A Randomized Controlled Trial. Patients under CBT needed significantly less analgesic tablets, and they achieved better responses in respect to depression and mental health than the controls. (The Haworth Press) Dircilene M. Falc. Journal of Musculoskeletal Pain. 10/20/08. |
| Effects of mud-bath treatment on fibromyalgia patients: a randomized clinical trial. A significant improvement after mud-bath therapy and after 16 weeks was observed. (IngentaConnet) Rheumatology International, Vol 27, No 12, Oct 2007, pp. 1157-1161(5). |
| Mindfulness meditation alleviates depressive symptoms in women with fibromyalgia: Results of a randomized clinical trial. Depressive symptoms improved significantly in treatment versus control participants over the 3 assessments. This meditation-based intervention alleviated depressive symptoms among patients with fibromyalgia. Wlley InterScience: Arthritis Care & Research Volume 57, Issue 1, Pages 77 - 85. (Also see: Alternative Remedies) |
| Acupuncture relieves symptoms of fibromyalgia, Mayo Clinic study finds. Evidence suggests acupuncture reduces the symptoms of fibromyalgia, according to a Mayo Clinic study. EurekaAlert! 06/14/06. (Also see: Alternative Therapies) |
| Musculoskeletal conditions and complementary/alternative medicine (CAM). Collectively the evidence demonstrates that some CAM modalities show significant promise, e.g. acupuncture, diets, herbal medicine, homoeopathy, massage, supplements. None of the treatments in question is totally devoid of risks. PubMed. Best Pract Res Clin Rheumatol. 2004 Aug;18(4):539-56. (Also see:Alternative Therapies) |
| Touch the pain away: new research on therapeutic touch and persons with fibromyalgia syndrome. Therapeutic touch may be an effective treatment for relieving pain and improving quality of life in this specific population of persons with fibromyalgia syndrome. PubMed. Holist Nurs Pract. 2004 May-Jun;18(3):142-51. |
| Electroconvulsive therapy (ECT) in patients with depression and fibromyalgia. We conclude that ECT is a safe and effective treatment for depression in fibromyalgia patients, but has no effect on the pain or other physical symptoms of these patients. PubMed. Eur J Pain. 2004 Aug;8(4):371-6. |
| A new treatment modality for fibromyalgia syndrome: hyperbaric oxygen therapy. We conclude that HBO therapy has an important role in managing FMS. PubMed. J Int Med Res. 2004 May-Jun;32(3):263-7. |
| Exercise |
| Effect of aerobic exercise training on oxygen uptake and kinetics in patients with fibromyalgia. The aim of this study was to investigate relation between cardiopulmonary performance and muscular microcirculation in patients with fibromyalgia syndrome (FMS). The results suggest that cardiopulmonary system in charge of delivering oxygen to whole body and muscular microcirculation may have dysfunction in patients with FMS. Mustafa Dinler. Rheumatology International (Springerlink). 09/28/09. |
| Cardiovascular Autonomic Modulation After Acute Resistance Exercise (RE) in Women With Fibromyalgia (FM). After acute RE, women with FM responded differently from controls. These postexercise responses may be attributed to the altered autonomic responsiveness to physiologic stress that characterizes FM. J.D. Kingsley. Archives of Physical Medicine and Rehabilitation. Volume 90, Issue 9, Pages 1628-1634 (September 2009). |
| Moderate Exercise Increases Expression for Sensory, Adrenergic, and Immune Genes in Chronic Fatigue Syndrome (CFS) Patients But Not in Normal Subjects. Muscle fatigue and pain are major symptoms of CFS. After moderate exercise, CFS and CFS-FMS (Fibromyalgia) patients show enhanced gene expression for receptors detecting muscle metabolites and for sympathetic nervous system, and immune system, which correlate with these symptoms. Alan R. Light. The Journal of Pain. 03 August 2009. (Also see: CFS) |
| Pool exercise for patients with fibromyalgia (FMS) or chronic widespread pain: A randomized controlled trial and subgroup analyses. The exercise-education programme showed significant, but small, improvement in health status in patients with FMS and chronic widespread pain, compared with education only. K. Mannerkorpi. Journal of Rehabilitation Medicine. September 2009. |
| A regular dip could benefit fibromyalgia sufferers. Patients suffering from fibromyalgia could benefit significantly from regular exercise in a heated swimming pool. EurekAlert! 02/21/08. |
| Exercise And Education Helps Women With Fibromyalgia. An exercise program that incorporates walking, strength training and stretching may improve daily function and alleviate symptoms in women with fibromyalgia, according to a new article. (ScienceDaily) JAMA and Archives Journals (2007, November 13). |
| Effects of Exercise in Warm Water on Pain and Cognitive Function in Middle-Aged Women with Fibromyalgia (FM). An exercise therapy three times per week for 16 weeks in a chest-high pool of warm water is an adequate treatment to decrease the pain and to improve cognitive function in previously unfit women with FM. D. Munguía-Izquierdo. OP0037-AHP EULAR 2007. (Also see: Pain Management) |
| From start to Fitness. Exercise can help in the management of fibromyalgia. Although it may be painful, the more that exercise is repeated over time, the greater the possibility of a decrease in symptoms. Union Sentinel. 04/12/06. |
| Exercise in waist-high warm water decreases pain and improves health-related quality of life and strength in the lower extremities in women with fibromyalgia. To evaluate the short- and long-term efficacy of exercise therapy in a warm, waist-high pool in women with fibromyalgia. The therapy relieved pain and improved HRQOL and muscle strength in the lower limbs at low velocity in patients with initial low muscle strength and high number of tender points. PubMed 02/15/06. |
| Medications |
| Treatment of fibromyalgia syndrome with gabapentin and pregabalin – A meta-analysis of randomized controlled trials. The efficacy of gabapentin and pregabalin in the treatment of fibromyalgia syndrome (FMS) was assessed. Five studies were suitable for meta-analysis. There was strong evidence for a non-substantial reduction of fatigue and of anxiety. Winfried Häuser. Pain. 18 June 2009. |
| Patients treated by tegaserod for irritable bowel syndrome with constipation showed significant improvement in fibromyalgia (FM) symptoms. A pilot study. The results of this pilot study provide the preliminary evidence that FM patients can benefit from treatment of tegaserod. (SpringerLink) Clinical Rheumatology. May 26 2009. |
| A Double Blind Clinical Trial: Treatment of Fibromyalgia (FM) in Post-Menopausal Women with Evista. Given the doses of medication used in this study, Raloxifen was superior to placebo in the treatment of menopausal patients with FM. S. Sadreddini. SAT0471. EULAR 2009. |
| Time of initial appearance of renal symptoms in the course of systemic lupus erythematosus (SLE) as a prognostic factor for lupus nephritis (LN). Onset time of LN in the course of SLE may affect renal prognosis. (SpringerLink) Y. Takahashi. Modern Rheumatology. March 10, 2009. (Also see: Lupus and Kidney Involvement) |
| Forest and Cypress Announce FDA Approval of Savella™ for the Management of Fibromyalgia. The studies showed that Savella doses of 100 mg/day and 200 mg/day demonstrated statistically significant and clinically meaningful concurrent improvements in pain, patient global assessment, and physical function. Savella is expected to be available in pharmacies by March 2009., Forest Laboratories, Inc.; Cypress Bioscience, Inc. 01/14/09. |
| Amitriptyline in the treatment of fibromyalgia (FM): a systematic review of its efficacy. There is some evidence to support the short-term efficacy of amitriptyline 25 mg/day in FM. There is no evidence to support the efficacy of amitriptyline at higher doses or for more than 8 weeks. B. Nishishinya. Rheumatology. August 12, 2008. |
| Efficacy of Milnacipran in Patients with Fibromyalgia. In this Phase II study, milnacipran led to statistically significant improvements in pain and other symptoms of FM. The effect sizes were equal to those previously found with TCA, and the drug was generally well tolerated. J Rheumatol. 2005 October;32:1975-85. |
| Fibromyalgia Syndrome: Review of Clinical Presentation, Pathogenesis, Outcome Measures, and Treatment. The multifaceted nature of FM suggests that multimodal individualized treatment programs may be necessary to achieve optimal outcomes in patients with this syndrome. J Rheumatol. 2005 August;32 Suppl 75:6-21. |
| A Randomized Controlled Trial of Dehydroepiandrosterone in Postmenopausal Women with Fibromyalgia. DHEA does not improve quality of life, pain, fatigue, cognitive function, mood, or functional impairment in FM. J Rheumatol. 2005 July;32;1336-40. |
| No Effect of Antiviral (Valacyclovir) Treatment in Fibromyalgia: A Double Blind, Randomized Study. Valacyclovir cannot be recommended as a therapy for FM at this point. J Rheumatol. April 2004;31:783-4. |
| Duloxetine May Be Effective for Treatment of Fibromyalgia Symptoms. Duloxetine, a drug being studied for treatment of depression, appears to be an effective and safe treatment for symptoms of fibromyalgia in patients with or without major depressive disorder (MDD), especially women, researchers said here on March 4th at the American Academy of Pain Medicine 20th Annual Meeting. Doctor's Guide. 03/05/04. |
| Nutrition |
| Hypothesis. Dietary Glutamate Will Not Affect Pain in Fibromyalgia. Based on present knowledge about glutamate consumption and its metabolism in humans, dietary reduction of glutamate will not accomplish pain relief in patients with FM. J Rheumatol. April 2004;31:785-7. |