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| Dermatomyositis and Polymyositis |
| This page was written by Shelley Ensz, and has not yet been medically edited. See Disclaimer. |
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| Symptoms of Dermatomyositis and Polymyositis |
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| Overview of Dermatomyositis and Polymyositis Symptoms |
| The main symptom of polymyositis (PM) is muscle weakness, primarily the skeletal muscle closet to the trunk. When the patient also has a rash, it is called dermatomyositis (DM). PM and DM patients usually have a difficult time geting up from a chair, raising the arms above the head to wash one's hair, and going up stairs. Other symptoms may fatigue and difficulty swallowing. ISN. |
| Symptoms of Dermatobyositis and Polymyositis. Weakness of muscles is the most common symptom of polymyositis. MedicineNet.com |
| Arterial Events in Persons with Dermatomyositis and Polymyositis. We found a high incidence of arterial events in this cohort of persons with inflammatory myopathy. A. Tissevereasinghe. JRheum. July 31 2009. |
| Interstitial lung disease (ILD) in polymyositis and dermatomyositis (PM/DM): Longitudinal evaluation by pulmonary function and radiology. ILD associated with PM/DM is in most cases mild, chronic, and has a nonprogressive course during immunosuppressive treatment. Myositis patients with ILD need careful evaluation of clinical features as well as Pulmonary function test and radiologic features during followup. (Wiley Interscience) Arthritis Care & Research 25 April 2008 (Also see: Pulmonary Fibrosis). |
| High-Resolution Computed Tomography Characterization of Interstitial Lung Diseases (ILD) in Polymyositis/dermatomyositis (PM/DM). The prognosis of ILD associated with DM differs from that with PM. Mortality rates were 12% and 44% for ILD associated with PM and DM, respectively. J Rheumatol 2008;35:260-9. |
| Proliferative vascular retinopathy in polymyositis and dermatomyositis with scleroderma (overlap syndrome). Retinal vascular occlusion with development of proliferative changes can occur in polymyositis/dermatomyositis. PubMed. Ocul Immunol Inflamm. 2007 Jan-Feb;15(1):45-9. (Also see: Eye Involvement) |
| Signs of inflammation in both symptomatic and asymptomatic muscles from patients with polymyositis and dermatomyositis. Presence of inflammatory infiltrates on muscle fibres were independent of clinical symptoms. Other factors seem to determine the development of clinical symptoms. Annals of the Rheumatic Diseases 2006;65:1565-1571. |
| Nailfold digital capillaroscopy in 447 patients with connective tissue disease and Raynaud's disease. The scleroderma capillary pattern is often present in SSc and dermato/polymyositis. Therefore, capillarmicroscopy seems to be a useful tool for the early selection of those patients who are potential candidates for developing scleroderma spectrum disorders. PubMed. J Eur Acad Dermatol Venereol. 2004 Jan;18(1):62-68. |
| Symptoms of Dermatomyositis |
| Symptoms of Dermatomyositis. The most common signs and symptoms of dermatomyositis include a violet-colored or dusky red rash and progressive muscle weakness. MayoClinic. |
| Dermatomyositis (DM) and small cell carcinoma of the bladder (SCCB). To the best of our knowledge, this is the first report of an association between SCCB and DM. L. Sagi, MD. Canadian Family Physician. October 2009. |
| Cutaneous lesions of dermatomyositis with supervening fibrosis. The identification of sclerosis in biopsies of skin lesions typical clinically for DM may be a harbinger for more severe autoimmune-based endothelial cell injury phenomenon. One could speculate that its basis may be attributable to elevated serum levels of the natural fibrogenic factor, transforming growth factor beta, which in turn is released from damaged endothelium. Magro CM. (PubMed) J Cutan Pathol. 2008 Jan;35(1):31-9. |
| Bilateral Ocular Myositis as a Late Complication of Dermatomyositis. We describe a 30-year-old man with a 2-month history of eyelid edema, erythema, and orbital pain, occurring in the course of previously undiagnosed and untreated dermatomyositis (DM). Although ocular myositis is a very rare manifestation of DM, it might be overlooked by clinicians who are not aware of this complication. J. Rheumatol No. 2 February 2005;32:379-81. |
| The Myositis Cutaneous Assessment Tool (MCAT): A New Approach to the Assessment of Cutaneous Disease and Damage in Adult and Juvenile Dermatomyositis. The MCAT is a new instrument that identifies and evaluates a broad range of skin findings in dermatomyositis with the purpose of establishing a standardized approach for recognizing and assessing cutaneous disease activity, severity and damage. E. Dugan. SP0100 EULAR 2003. |
| A rare complication of generalized edema in juvenile dermatomyositis: a report of one case. Magnetic resonance imaging (MRI) of the lower extremities and pelvis showed marked diffuse edema in the subcutaneous tissue, muscles and myofascia. We suggest that MRI findings, which are not among the diagnostic criteria, may also be included in the diagnostic criteria of JDM. PubMed. Brain Dev. 2004 Jun;26(4):269-72. |
| Severe Central Nervous System (CNS) Involvement in Juvenile Dermatomyositis. Although rarely reported, CNS vasculopathy can be a serious and life-threatening complication of JDM. J Rheumatology. Volume 30: No. 9 September 2003;30:2059-63. |
| Symptoms of Polymyositis |
| Symptoms of Polymyositis. Progressive muscle weakness is the most common polymyositis symptom.Signs and symptoms of polymyositis usually appear gradually and may fluctuate day to day, month to month. MayoClinic. |
| Exploratory Analysis of the Relationships between Aerobic Capacity and Self-Reported Fatigue in Patients with Rheumatoid Arthritis (RA), Polymyositis (PM), and Chronic Fatigue Syndrome (CFS). This study confirms that patients with chronic, but stable RA, PM, or CFS are fatigued and have significantly decreased aerobic capacity. A. Weinstein. PM &R. July 2009. (Also see: RA and CFS) |
| Polymyositis with dysphagia treated with endoscopic balloon dilatation. We report a case of an 80-year-old man who was referred to our clinic with a chief complaint of dysphagia and muscle weakness in all four limbs. The patient was diagnosed with polymyositis. Endoscopic balloon dilation was performed and dysphagia improved on the same day. Therefore, we suggest that this method is a safe and effective approach for polymyositis with dysphagia. (PubMed) H. Nagano. Auris Nasus Larynx. May 28 2009. |
| Role of Endothelial Damage in the Pathogenesis of Interstitial Pneumonitis in Patients with Polymyositis and Dermatomyositis. Our data suggest that endothelial damage might play an important role through the production of fibrosis-enhancing factors such as TGF-ß or ET-1 in PM/DM. J Rheumatol 2006 May;33:903-6. (Also see: Pulmonary Involvement) |
