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Systemic Scleroderma Symptoms: MAIN PAGE
These symptoms may occur in systemic scleroderma (systemic sclerosis) but usually not in localized scleroderma, such as linear or morphea scleroderma. See Types of Scleroderma. Nearly all of these symptoms may occur alone or as part of other illnesses besides scleroderma, particularly including other arthritis or autoimmune diseases or in scleroderma-like illnesses. Just because an item is listed here does not mean that it will occur in any given case, as there are many different types of scleroderma, which vary greatly in regard to both symptoms and severity. Consult a rheumatologist or scleroderma expert for diagnosis of scleroderma or related illnesses.
Associated Conditions
Brain
Dental/Mouth
Eyes
Fatigue 		Gastrointestinal
Heart (Cardiac)
Kidney (Renal)
Liver
Lung (Pulmonary) 		Photos of Symptoms
Pregnancy
Raynaud's
Similar Skin Diseases 		Sjogren's Syndrome
Skeletal (Bones, Joints Muscles)
Skin and Hair
Identification Of Major Heath Problems Of Patients With Limited Systemic Sclerosis And Diffuse Systemic Sclerosis - Ailments Reported By Patients Versus Diagnostic Tests. Joint pain, which is characteristic for early SSc as well as ulceration and finger dysaesthesia may cause significant difficulties in self-care activities; alimentary tract problems affect mainly lSSc patients; SSc-related lung lesions are more often observed in dSSc patients. Subjective symptoms do not always indicate the progression of lesions observed in diagnostic tests. M. Sierakowska FRI0507-AHP EULAR 2008.
Associated Conditions
Anemia of Chronic Disease
Antiphospholipid Syndrome
Ankylosing Spondylitis
Arthritis
Asthma
Autoimmunity
Behcet's
Cancer
Celiac Disease
Chronic Fatigue Syndrome
Depression
Dermatology (General)
Dermatomyositis 		Diabetes
Ear Diseases, Autoimmune
Ehlers-Danlos syndromes (EDS)
Endometriosis
Eye Diseases, Autoimmune
Fatigue
Fibromyalgia
Glaucoma/Retinal Involvement
Guillain-Barre
Idiopathic Thromocytopenic Purpura
Interstitial Cystitis 		Leukemia
Marfan syndrome (MFS)
MCTD
Multiple Sclerosis
Myasthenia Gravis
Neuromuscular Diseases
Pancytopenia
Polyarteritis Nodosa
Polymyositis
Psoriasis, PsA
Rheumatoid Arthritis
Sarcoidosis 		Scleroderma
Similar Skin Diseases
Systemic Lupus (SLE)
Thrombotic Purpura (TTP)
Thyroid Disease
TB & Scleroderma
Tuberculous Fasciitis
UCTD
Vasculitis
Vulvodynia
 Wegener's Granulomatosis
Brain
Overview of Brain Involvement
Steroids/Brain Atrophy 		Systemic Scleroderma
—Vascular Headache 		—What is Vertigo?
Localized Scleroderma 		Personal Stories
Related Links
Dental/Mouth Symptoms in Systemic Scleroderma
Overview of Dental Involvement
Bone Reabsorption of the Mandible
Candida (Fungal)
Cavities 		Dental Amalgam
Dental Fears/Phobias
Dental Implants
Denture Problems
Microstomia (Small Mouth)
 Periodontal Disease
Sensitive Teeth
Sjogren's Syndrome
TMJ
Tongue Cancer 		Trigeminal Neuralgia
Xerostomia (Dry Mouth)
Personal Stories
Related Books
Eye Involvement in Systemic Scleroderma
Scleroderma Eye Involvement
Dry Eyes
Normal Tension Glaucoma (NTG) 		NTG Symptoms/Diagnosis
NTG Treatments 		Autoimmune Iritis or Uveitis
Eye Support Groups 		Personal Stories
Related Pages
Media Stories
Fatigue in Systemic Scleroderma
Overview of Fatigue
Causes of Fatigue
Coping with Fatigue
Scleroderma Complications and Fatigue 		Treatments for Fatigue
Personal Stories
Related Links
Gastrointestinal Symptoms in Systemic Scleroderma
Overview of G.I. Involvement
Bowel Dysfunction 		Dysphagia (Swallowing)
Esophageal (Throat) 		Esophagus: Heartburn
Gastroparesis 		G.A.V.E. (Watermelon Stomach)
Heart (Cardiac) Involvement in Systemic Scleroderma
Overview
Antiphospholipid
Scleroderma 		Complications
Heart Symptoms 		Diagnosis
Treatments 		Research
Patient & Caregiver Stories
Kidney Involvement in Systemic Scleroderma
Kidney (Renal) Involvement Kidney (Renal) Dialysis and Transplant
Liver Symptoms in Systemic Scleroderma
Overview
Hepatitis, Autoimmune
Hepatitis C (Viral Hepatitis) 		Cancer of Liver
Cirrhosis of Liver
Biliary Cirrhosis Symptoms 		Biliary Cirrhosis Diagnosis
Primary Biliary Cirrhosis 		Personal Stories
Support Groups
Spleen
Lung Symptoms in Systemic Scleroderma
Lung (Pulmonary) Overview
Aspiration Pneumonia 		Oxygen Therapy
Pleural Effusion 		Pulmonary Fibrosis
Pulmonary Hypertension 		Preventive Care
Pulmonary Support Resources
Photos of Localized and Systemic Scleroderma Symptoms
ISN Photo Donation Form
Alopecia
Calcinosis
CREST Syndrome 		Gangrene
Localized (Linear/Morphea)
Overlap Syndrome 		Raynaud's
Scleredema
Sclerodactyly
Skin Ulcers 		Sympathectomy Surgery
Systemic Scleroderma
Watermelon Stomach
Pregnancy and Systemic Scleroderma
Autoimmunity and Pregnancy
Autoimmunity and Menopause
Antidepressants/Fetal P.H. 		Preeclampsia
Congenital Heart Block in Fetuses
Male Infertility 		Medications and Pregnancy
Scleroderma and Pregnancy
—Slide Show 		Smoking and Pregnancy
Personal Stories
Related Information
Raynaud's
What is Raynaud's?
Diagnosis
Treatments 		Medications
Improving Circulation
Prevention
 Rewarming Tips
Heatsock Directions
Tips from Patients
 Research
Patient Support
Patient Stories
Similar Skin Diseases
Skin Diseases Similar to Scleroderma (Main Menu)
Skin Diseases (Main Page)
About Dermatology
Acrokeratoelastoidosis
Atrophoderma Pierini/Pasini
Bullous Pemphigoid
CREST Syndrome
Dermatitis Artefacta
Diffuse Scleroderma
Eosinophilia Myalgia (EMS)
Eosinophilic Fasciitis 		Graft-Versus-Host-Disease
Grzybowski Syndrome
Keloidal Scleroderma
Lichen Sclerosus
Linear Scleroderma
Limited Systemic Scleroderma
Lipodermatosclerosis
Lipodystrophy, Lipoatrophy
 Morphea
Myeloma (Bone Cancer)
Nephrogenic Fibrosing Derm
Overlap/UCTD/MCTD
Parry-Rombergs Syndrome
Pemphigus Vulgaris
POEMS
Porphyria Cutanea Tarda
Progeria 		Pseudoscleroderma
Radiation Port Scleroderma
Scleredema Adultorum Buschke
Scleroderma
Scleroderma-Like
Scleromyxedema
Stiff Skin Syndrome
Vitiligo
Werner's Syndrome
Sjögren's Syndrome
What is Sjögren's?
Symptoms of Sjogren's
Diagnosis of Sjogren's
Similar & Overlaps 		Treatments for Sjögren's
—Overview of Treatments
—Treatments for Dry Eyes
—Treatments for Dry Mouth 		Sjogren's Research
—Overview of Research
—Antibodies
—Brain Involvement
—Causes 		—Dry Eyes
Online Support
Personal Stories
Media Stories
Skeletal Involvement
Overview
Body Fat Composition
Bone Reabsorption
Erosive Arthropathy 		Joint Contractures
Joints, Carpal Tunnel
Myositis (Muscle Inflammation) 		Neurological
Osteoporosis
Transverse Myelitis 		Patient Stories: Skeletal
Patient Stories: Osteoporosis
Skin and Hair
Association with Other Symptoms
Alopecia (Hair Loss)
Calcinosis
Collagen Injections, Face Lifts and Scleroderma
Digital (Finger) Ulcers 		Edema (Swelling)
Elbow Tip Pain
Fibrosis (Tightening/Hardening)
Fingernails, Nailfolds, Cuticles
Gangrene (Death of Tissue) 		Hyperpigmentation
Itching
Microstomia
Neck Sign
Raynaud's 		Rashes
Sclerodactyly
Telangiectasia
Xerosis (Dry Skin)
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