Causes of Scleroderma: Environmental |
| Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer |
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Overview of Environmental Causes of Systemic Sclerosis |
| Topics covered include exposure to cadmium, mercury (dental amalgam), solvents (such as paint thinners), radiation, and silica as either known or suspected causes of autoimmune diseases or scleroderma. (Also see: Causes of Scleroderma, What is Scleroderma?, Types of Scleroderma, and Systemic Sclerosis) |
| Requirements for innate immune pathways in environmentally induced autoimmunity. These findings from several environmentally induced models suggest that environmental triggers can induce autoimmunity through diverse innate pathways. BMC Medicine 2013, 11:100. (Also see: Causes of Scleroderma: Environmental) |
Artificial Joints and Silicone Breast Implants |
| Causes of Scleroderma: Artificial Joints and Silicone Breast Implants. Are some cases of connective tissue disease, such as scleroderma, related to artificial joints or silicone breast implants? ISN. |
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Asbestos |
| Asbestos exposure is a possible cause of scleroderma. |
| The worldwide pandemic of asbestos-related diseases. Asbestos-related diseases are still a major public health problem. The World Health Organization (WHO) has estimated that 107,000 people worldwide die each year from mesothelioma, lung cancer, and asbestosis. Annu Rev Public Health, 2013;34:205-16. |
| Fight Mesothelioma. Mesothelioma has only one cause: asbestos. We will help you explore your legal options if your health has been affected by asbestos exposure. The Law Firm of Baron and Budd. |
Air Pollution |
| Air pollution in autoimmune rheumatic diseases: A review. Other diseases such as scleroderma may be triggered by the inhalation of chemical solvents, herbicides and silica. Autrev, 2011.06.008. |
Drugs and Medications |
| Causes of Scleroderma: Drugs and Medications Some medications and street drugs are known or thought to induce scleroderma or Raynaud's, such as Bleomycin, Cocaine, Marijuana, and Paclitaxel (Taxanes). ISN. |
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Environmental Toxins |
| Air pollution in autoimmune rheumatic diseases: A review. This paper reviews the mechanisms of air contaminants influencing the immune response and autoimmunity. Farhat SC. (PubMed) Autoimmun Rev, 2011 Jul 6. (Also see: Rheumatic Diseases) |
| Phyllis C: Scleroderma How many new cases are coming up now from people that were at the World Trade Center? I was there along with co-workers that are very ill now... |
Infection |
| Causes of Scleroderma: Infections Researchers have long suspected an infection component may be involved as the trigger of some cases of scleroderma. ISN. |
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Mercury Exposure (Dental Amalgam) |
| Causes of Scleroderma: Mercury Exposure (Dental Amalgam) covers recent research indicating that there may be a link between mercury exposure and autoimmune diseases. ISN. |
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Radiation |
| Radiation and Scleroderma. There is an increased rate of cancer among scleroderma patients. ISN. |
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Silica |
| Silica Exposure. Silica exposure can cause autoimmune diseases such as lupus, scleroderma, and vasculitis. ISN. |
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Solvents (Benzene, Trichloroethylene, Paint Thinners and Removers) |
| Causes of Scleroderma: Solvents. Occupational exposure to solvents such as benzene, trichloroethylene, paint thinners and paint removers may be a cause of scleroderma in some cases. ISN. |
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Vaccinations |
| Causes of Scleroderma: Vaccinations. Vaccinations have been suspected as a cause of scleroderma, in a few cases. ISN. |
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Vinyl Chloride and Vinyl Choride Disease |
| Causes of Scleroderma: Vinyl Chloride Exposure to vinyl chloride has been found to cause acroosteolysis, angiosarcoma, brain cancer, leukemia, liver disease, Raynaud's, scleroderma, and "vinyl chloride disease". ISN. |
Personal Stories Related to Environmental Exposures |
| Marthie D: CREST Scleroderma I live in a small town, which developed around a chemical and petrochemical industry in this area in South Africa... |